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WASH3P WASP family homolog 3, pseudogene [ Homo sapiens (human) ]

Gene ID: 374666, updated on 25-Jan-2022

Summary

Official Symbol
WASH3Pprovided by HGNC
Official Full Name
WASP family homolog 3, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:24362
See related
AllianceGenome:HGNC:24362
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM39DP
Summary
Predicted to enable alpha-tubulin binding activity. Involved in several processes, including Arp2/3 complex-mediated actin nucleation; early endosome to late endosome transport; and protein targeting to lysosome. Located in endosome; filopodium; and lamellipodium. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in testis (RPKM 26.3), spleen (RPKM 26.3) and 25 other tissues See more
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Genomic context

See WASH3P in Genome Data Viewer
Location:
15q26.3
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (101960813..101976605)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (102501016..102516808)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 138 member E Neighboring gene microRNA 1302-10 Neighboring gene microRNA 6859-3 Neighboring gene DEAD/H-box helicase 11 like 9 (pseudogene)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • WAS protein family homolog 3, pseudogene
  • family with sequence similarity 39, member D pseudogene

Clone Names

  • FLJ25222, FLJ57306, FLJ75027, FLJ77846, FLJ78059, MGC52000, MGC117230

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables alpha-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables alpha-tubulin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables gamma-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in Arp2/3 complex-mediated actin nucleation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in early endosome to late endosome transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endocytic recycling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in endosomal transport ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in endosome organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to lysosome IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in retrograde transport, endosome to Golgi IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retrograde transport, endosome to Golgi ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of WASH complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of WASH complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in autophagosome IEA
Inferred from Electronic Annotation
more info
 
located_in centriole IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in early endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in filopodium IDA
Inferred from Direct Assay
more info
PubMed 
located_in lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in recycling endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in recycling endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in recycling endosome ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in recycling endosome membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003659.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC140725, AK056232, AK057951, AW604905, BQ722707, BQ935819, BQ937971, DA065132

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    101960813..101976605
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_021160015.1 Reference GRCh38.p13 PATCHES

    Range
    66950..82742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_199163.2: Suppressed sequence

    Description
    NM_199163.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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