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MBL2 mannose binding lectin 2 [ Gallus gallus (chicken) ]

Gene ID: 374267, updated on 25-May-2017
Symbol
MBL2provided by CGNC
Full Name
mannose binding lectin 2provided by CGNC
Primary source
CGNC:49110
See related
Ensembl:ENSGALG00000002507
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MBL; MBP; cMBl; collectin
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
103 current Gallus_gallus-5.0 (GCF_000002315.4) 6 NC_006093.4 (4503081..4511261, complement)
102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) 6 NC_006093.3 (3981178..3989357, complement)

Chromosome 6 - NC_006093.4Genomic Context describing neighboring genes Neighboring gene surfactant protein A1 Neighboring gene surfactant protein A2 Neighboring gene uncharacterized LOC101752294 Neighboring gene uncharacterized LOC101752332

  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calcium-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 
mannose binding IEA
Inferred from Electronic Annotation
more info
 
receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
complement activation TAS
Traceable Author Statement
more info
 
complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 
complement activation, lectin pathway TAS
Traceable Author Statement
more info
 
defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 
negative regulation of growth of symbiont in host IEA
Inferred from Electronic Annotation
more info
 
negative regulation of viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
collagen trimer IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
mannose-binding lectin; pulmonary surfactant-associated protein D
Names
c-type lectin
mannan-binding lectin
mannan-binding protein
mannose binding lectin, liver (A)
mannose-binding lectin (protein C) 2, soluble
mannose-binding protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204349.2NP_989680.2  mannose-binding lectin precursor

    Status: VALIDATED

    Source sequence(s)
    AADN04000143
    UniProtKB/Swiss-Prot
    Q98TA4
    Related
    ENSGALP00000040351.1, ENSGALT00000041145.3
    Conserved Domains (3) summary
    cd03591
    Location:142254
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
    pfam01391
    Location:47102
    Collagen; Collagen triple helix repeat (20 copies)
    pfam09006
    Location:105149
    Surfac_D-trimer; Lung surfactant protein D coiled-coil trimerization

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gallus_gallus-5.0 Primary Assembly

Genomic

  1. NC_006093.4 Reference Gallus_gallus-5.0 Primary Assembly

    Range
    4503081..4511261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015287953.1XP_015143439.1  pulmonary surfactant-associated protein D isoform X2

    Conserved Domains (3) summary
    cd03591
    Location:126238
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
    pfam01391
    Location:3184
    Collagen; Collagen triple helix repeat (20 copies)
    pfam09006
    Location:89133
    Surfac_D-trimer; Lung surfactant protein D coiled-coil trimerization
  2. XM_015287952.1XP_015143438.1  pulmonary surfactant-associated protein D isoform X1

    Conserved Domains (3) summary
    cd03591
    Location:111223
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
    pfam01391
    Location:1671
    Collagen; Collagen triple helix repeat (20 copies)
    pfam09006
    Location:74118
    Surfac_D-trimer; Lung surfactant protein D coiled-coil trimerization
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