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TGFBR3 transforming growth factor beta receptor 3 [ Gallus gallus (chicken) ]

Gene ID: 374251, updated on 16-Jun-2026
Symbol
TGFBR3provided by CGNC
Full Name
transforming growth factor beta receptor 3provided by CGNC
Primary source
CGNC:4525
See related
Ensembl:ENSGALG00010022082
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See TGFBR3 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (14078489..14188389)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (14085041..14195063)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene bromodomain testis-specific protein-like Neighboring gene bromodomain testis associated Neighboring gene uncharacterized LOC121111434 Neighboring gene translation initiation factor IF-2-like Neighboring gene cell division cycle 7 Neighboring gene HFM1, ATP dependent DNA helicase homolog

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Messenger RNA and protein expression analysis of betaglycan in the pituitary and ovary of the domestic hen. Sweeney SA, et al. Biol Reprod, 2005 Jan. PMID 15385424
  2. Regulation of H(2)S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process. Qianru C, et al. J Hazard Mater, 2021 Mar 15. PMID 33307448
  3. Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC. Townsend TA, et al. Cell Signal, 2012 Jan. PMID 21945156, Free PMC Article
  4. Expression of the type III TGFbeta receptor during chick organogenesis. Olivey HE, et al. Anat Rec A Discov Mol Cell Evol Biol, 2003 May. PMID 12704694
  5. Multiple transforming growth factor-beta isoforms and receptors function during epithelial-mesenchymal cell transformation in the embryonic heart. Mercado-Pimentel ME, et al. Cells Tissues Organs, 2007. PMID 17587820

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process.
    Title: Regulation of H(2)S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process.
  2. TGFB ligands and receptors show dynamic and frequently overlapping expression patterns in numerous embryonic cell layers and structures
    Title: Embryonic expression of the transforming growth factor beta ligand and receptor genes in chicken.
  3. the cytoplasmic domain of TGFbeta receptor 3, specifically the 3 C-terminal amino acids required to bind GIPC, were required for TGFbeta-2 and bone morphogenetic protein-2 stimulated epithelial-mesenchymal transformation
    Title: Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC.
  4. Data show that TGF-beta1, -beta2, and -beta3 and their receptors have distinct spatiotemporal developmental protein localization patterns in the developing tendon and suggest that these isoforms have independent roles in tendon development.
    Title: Spatiotemporal protein distribution of TGF-betas, their receptors, and extracellular matrix molecules during embryonic tendon development.
  5. expression of betaglycan mRNA in the anterior pituitary, consistent with known inhibin effects. Ovarian localization of betaglycan, particularly in the theca layer, suggests a paracrine role for inhibin
    Title: Messenger RNA and protein expression analysis of betaglycan in the pituitary and ovary of the domestic hen.
Submit: New GeneRIF Correction

Homology

Preferred Names
transforming growth factor beta receptor type 3
Names
transforming growth factor, beta receptor III (betaglycan, 300kDa)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204339.2 → NP_989670.1  transforming growth factor beta receptor type 3 precursor

    See identical proteins and their annotated locations for NP_989670.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000239
    UniProtKB/TrEMBL
    A0A8V0ZLM6, A0A8V0ZNT3, Q90998
    Related
    ENSGALP00010032349.1, ENSGALT00010053708.1
    Conserved Domains (1) summary
    smart00241
    Location:446 → 718
    ZP; Zona pellucida (ZP) domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14078489..14188389
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040704478.2 → XP_040560412.1  transforming growth factor beta receptor type 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZLM6, A0A8V0ZNT3, Q90998
    Conserved Domains (1) summary
    smart00241
    Location:446 → 718
    ZP; Zona pellucida (ZP) domain

  2. XM_040704479.2 → XP_040560413.1  transforming growth factor beta receptor type 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZLM6, A0A8V0ZNT3, Q90998
    Conserved Domains (1) summary
    smart00241
    Location:446 → 718
    ZP; Zona pellucida (ZP) domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    14085041..14195063
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046922229.1 → XP_046778185.1  transforming growth factor beta receptor type 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZLM6, A0A8V0ZNT3, Q90998

  2. XM_046922230.1 → XP_046778186.1  transforming growth factor beta receptor type 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZLM6, A0A8V0ZNT3, Q90998
Nucleotide Protein
Heading Accession and Version

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