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CRHR1 corticotropin releasing hormone receptor 1 [ Gallus gallus (chicken) ]

Gene ID: 374218, updated on 17-Aug-2024
Symbol
CRHR1provided by CGNC
Full Name
corticotropin releasing hormone receptor 1provided by CGNC
Primary source
CGNC:216
See related
Ensembl:ENSGALG00010022705
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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See CRHR1 in Genome Data Viewer
Location:
chromosome: 27
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 27 NC_052558.1 (1880796..1906670)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 27 NC_052599.1 (3098585..3124454)

Chromosome 27 - NC_052558.1Genomic Context describing neighboring genes Neighboring gene SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 Neighboring gene acid sensing ion channel subunit 2 Neighboring gene uncharacterized LOC121107703 Neighboring gene zona pellucida-binding protein 2-like Neighboring gene reprimo like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Molecular cloning of a type A chicken corticotropin-releasing factor receptor with high affinity for urotensin I. Yu J, et al. Endocrinology, 1996 Jan. PMID 8536612
  2. Involvement of thyrotropin-releasing hormone receptor, somatostatin receptor subtype 2 and corticotropin-releasing hormone receptor type 1 in the control of chicken thyrotropin secretion. De Groef B, et al. Mol Cell Endocrinol, 2003 May 30. PMID 12782401
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CRHR1 expression is virtually confined to corticotropes, suggesting that CRH-induced adrenocorticotropin release is the result of a direct stimulation of corticotropes, whereas CRH-stimulated TSH release is not directly mediated by the known chicken CRHR1
    Title: Involvement of thyrotropin-releasing hormone receptor, somatostatin receptor subtype 2 and corticotropin-releasing hormone receptor type 1 in the control of chicken thyrotropin secretion.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotrophin-releasing factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables corticotropin-releasing hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
corticotropin-releasing factor receptor 1
Names
CRF-R-1
CRF-R1
CRFR-1
CRH-R-1
CRH-R1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204321.2 → NP_989652.2  corticotropin-releasing factor receptor 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000363
    UniProtKB/Swiss-Prot
    Q90812
    UniProtKB/TrEMBL
    F1NS14
    Related
    ENSGALP00010033414.1, ENSGALT00010055228.1
    Conserved Domains (2) summary
    smart00008
    Location:45 → 116
    HormR; Domain present in hormone receptors
    cd15445
    Location:121 → 385
    7tmB1_CRF-R1; corticotropin-releasing factor receptor 1, member of the class B family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052558.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1880796..1906670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052599.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    3098585..3124454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q90812.1 GenPept UniProtKB/Swiss-Prot:Q90812

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.