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QKI QKI, KH domain containing RNA binding [ Gallus gallus (chicken) ]

Gene ID: 374204, updated on 20-Jun-2026
Symbol
QKIprovided by CGNC
Full Name
QKI, KH domain containing RNA bindingprovided by CGNC
Primary source
CGNC:8781
See related
Ensembl:ENSGALG00010006041
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See QKI in Genome Data Viewer
Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (43784462..43923838, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (43690995..43830374, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532166 Neighboring gene uncharacterized LOC107053062 Neighboring gene uncharacterized LOC121110378 Neighboring gene PARK2 coregulated

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Four isoforms of the signal-transduction and RNA-binding protein QKI expressed during chicken spermatogenesis. Mezquita J, et al. Mol Reprod Dev, 1998 May. PMID 9547512
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
KH domain-containing RNA-binding protein QKI
Names
protein quaking
RNA binding/signal transduction protein QkI-2
homolog of mouse quaking QKI (KH domain RNA binding protein)
quaking homolog, KH domain RNA binding

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204310.3 → NP_989641.2  KH domain-containing RNA-binding protein QKI

    See identical proteins and their annotated locations for NP_989641.2

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000063
    UniProtKB/Swiss-Prot
    Q9PST2, Q9YH18, Q9YH19, Q9YH20
    UniProtKB/TrEMBL
    A0A8V0XWS7
    Related
    ENSGALP00010008493.1, ENSGALT00010014472.1
    Conserved Domains (4) summary
    PHA03247
    Location:212 → 313
    PHA03247; large tegument protein UL36; Provisional
    cd02395
    Location:83 → 205
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:313 → 340
    Quaking_NLS; Putative nuclear localization signal of quaking

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    43784462..43923838 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015284003.4 → XP_015139489.1  protein quaking isoform X8

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Conserved Domains (4) summary
    PRK14950
    Location:195 → 304
    PRK14950; DNA polymerase III subunits gamma and tau; Provisional
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:303 → 332
    Quaking_NLS; Putative nuclear localization signal of quaking
    cd22465
    Location:81 → 183
    KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

  2. XM_040696716.2 → XP_040552650.1  protein quaking isoform X5

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Related
    ENSGALP00010008491.1, ENSGALT00010014469.1
    Conserved Domains (1) summary
    COG5176
    Location:83 → 206
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  3. XM_040696715.2 → XP_040552649.1  protein quaking isoform X14

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (2) summary
    COG5176
    Location:83 → 221
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
    PRK14950
    Location:210 → 319
    PRK14950; DNA polymerase III subunits gamma and tau; Provisional

  4. XM_015284000.4 → XP_015139486.1  protein quaking isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (4) summary
    cd02395
    Location:83 → 220
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam07777
    Location:247 → 292
    MFMR; G-box binding protein MFMR
    pfam16544
    Location:10 → 68
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:328 → 355
    Quaking_NLS; Putative nuclear localization signal of quaking

  5. XM_015284001.4 → XP_015139487.1  protein quaking isoform X4

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (4) summary
    PRK14950
    Location:212 → 321
    PRK14950; DNA polymerase III subunits gamma and tau; Provisional
    cd02395
    Location:83 → 222
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:322 → 349
    Quaking_NLS; Putative nuclear localization signal of quaking

  6. XM_015283999.4 → XP_015139485.1  protein quaking isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (3) summary
    cd02395
    Location:83 → 222
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:329 → 356
    Quaking_NLS; Putative nuclear localization signal of quaking

  7. XM_015283998.4 → XP_015139484.1  protein quaking isoform X1

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (4) summary
    PHA03247
    Location:229 → 330
    PHA03247; large tegument protein UL36; Provisional
    cd02395
    Location:83 → 222
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    pfam16551
    Location:330 → 357
    Quaking_NLS; Putative nuclear localization signal of quaking

  8. XM_040696721.2 → XP_040552655.1  protein quaking isoform X12

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Conserved Domains (2) summary
    COG5176
    Location:83 → 206
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]
    PRK14950
    Location:195 → 288
    PRK14950; DNA polymerase III subunits gamma and tau; Provisional

  9. XM_040696720.2 → XP_040552654.1  protein quaking isoform X11

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Conserved Domains (3) summary
    pfam07777
    Location:210 → 276
    MFMR; G-box binding protein MFMR
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    cd22465
    Location:81 → 183
    KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

  10. XM_040696722.2 → XP_040552656.1  protein quaking isoform X13

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Conserved Domains (1) summary
    COG5176
    Location:83 → 206
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  11. XM_040696719.2 → XP_040552653.1  protein quaking isoform X10

    UniProtKB/TrEMBL
    A0A8V0XWS7
    Conserved Domains (2) summary
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein
    cd22465
    Location:81 → 183
    KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

  12. XM_015284004.4 → XP_015139490.1  protein quaking isoform X9

    UniProtKB/TrEMBL
    A0A8V0XJY9, A0A8V0XU17
    Related
    ENSGALP00010008488.1, ENSGALT00010014464.1
    Conserved Domains (3) summary
    cd02395
    Location:83 → 222
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam07777
    Location:241 → 286
    MFMR; G-box binding protein MFMR
    pfam16544
    Location:10 → 68
    STAR_dimer; Homodimerization region of STAR domain protein

  13. XM_040696717.2 → XP_040552651.1  protein quaking isoform X7

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Conserved Domains (1) summary
    COG5176
    Location:83 → 223
    MSL5; Splicing factor (branch point binding protein) [RNA processing and modification]

  14. XM_015284002.4 → XP_015139488.1  protein quaking isoform X6

    UniProtKB/TrEMBL
    A0A8V0XJY9
    Related
    ENSGALP00010008485.1, ENSGALT00010014460.1
    Conserved Domains (2) summary
    cd02395
    Location:83 → 222
    SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
    pfam16544
    Location:10 → 66
    STAR_dimer; Homodimerization region of STAR domain protein

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    43690995..43830374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046912900.1 → XP_046768856.1  protein quaking isoform X8

    UniProtKB/TrEMBL
    A0A8V0XWS7

  2. XM_046912897.1 → XP_046768853.1  protein quaking isoform X5

    UniProtKB/TrEMBL
    A0A8V0XWS7

  3. XM_046912895.1 → XP_046768851.1  protein quaking isoform X3

    UniProtKB/TrEMBL
    A0A8V0XJY9

  4. XM_046912896.1 → XP_046768852.1  protein quaking isoform X4

    UniProtKB/TrEMBL
    A0A8V0XJY9

  5. XM_046912894.1 → XP_046768850.1  protein quaking isoform X2

    UniProtKB/TrEMBL
    A0A8V0XJY9

  6. XM_046912893.1 → XP_046768849.1  protein quaking isoform X1

    UniProtKB/TrEMBL
    A0A8V0XJY9

  7. XM_046912904.1 → XP_046768860.1  protein quaking isoform X12

    UniProtKB/TrEMBL
    A0A8V0XWS7

  8. XM_046912903.1 → XP_046768859.1  protein quaking isoform X11

    UniProtKB/TrEMBL
    A0A8V0XWS7

  9. XM_046912905.1 → XP_046768861.1  protein quaking isoform X13

    UniProtKB/TrEMBL
    A0A8V0XWS7

  10. XM_046912902.1 → XP_046768858.1  protein quaking isoform X10

    UniProtKB/TrEMBL
    A0A8V0XWS7

  11. XM_046912901.1 → XP_046768857.1  protein quaking isoform X9

    UniProtKB/TrEMBL
    A0A8V0XJY9, A0A8V0XU17

  12. XM_046912899.1 → XP_046768855.1  protein quaking isoform X7

    UniProtKB/TrEMBL
    A0A8V0XJY9

  13. XM_046912898.1 → XP_046768854.1  protein quaking isoform X6

    UniProtKB/TrEMBL
    A0A8V0XJY9
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9YH18.2 GenPept UniProtKB/Swiss-Prot:Q9YH18

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