ME1 malic enzyme 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: ME1provided by CGNC
Full Name: malic enzyme 1provided by CGNC
Primary source: CGNC:49075
See related: Ensembl:ENSGALG00010002972
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: NADP-ME
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	3	NC_052534.1 (77460209..77617692)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	3	NC_052575.1 (77251745..77409468)

Chromosome 3 - NC_052534.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that expression of malic enzyme (ME), fatty acid synthase (FAS) and acetyl coenzyme carboxylase (ACC) genes was decreased by feeding a 30% protein diet (acute or chronic feeding).
Title: Further studies on short-term adaptations in the expression of lipogenic genes in broilers.

Submit: New GeneRIF Correction

General gene information

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Markers

ME1sts1 (e-PCR), detects polymorphism
- UniSTS:280209

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info	PubMed
enables malate dehydrogenase (decarboxylating) (NAD+) activity	IEA Inferred from Electronic Annotation more info	PubMed
enables malate dehydrogenase (decarboxylating) (NADP+) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in malate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in pyruvate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NADP-dependent malic enzyme

Names: malate dehydrogenase; malic enzyme 1, NADP(+)-dependent, cytosolic

NP_989634.2

EC 1.1.1.40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_204303.2 → NP_989634.2 NADP-dependent malic enzyme

Status: VALIDATED

Source sequence(s)

JAENSK010000065

UniProtKB/TrEMBL

F1P0Y6, Q90XC0

Related

ENSGALP00010004234.1, ENSGALT00010006963.1

Conserved Domains (1) summary

PLN03129
Location:21 → 561

PLN03129; NADP-dependent malic enzyme; Provisional