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DKK4 dickkopf WNT signaling pathway inhibitor 4 [ Gallus gallus (chicken) ]

Gene ID: 374156, updated on 17-Aug-2024
Symbol
DKK4provided by CGNC
Full Name
dickkopf WNT signaling pathway inhibitor 4provided by CGNC
Primary source
CGNC:2791
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
DKK1
Orthologs
human mouse all
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See DKK4 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (10957318..10958457)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (10828419..10829860)

Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene APOBEC1 complementation factor Neighboring gene protein kinase, cGMP-dependent, type I Neighboring gene uncharacterized LOC112532686 Neighboring gene uncharacterized LOC121111143 Neighboring gene uncharacterized LOC124418085

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Inhibition of Wnt/β-catenin pathway by Dickkopf-1 [corrected] affects midfacial morphogenesis in chick embryo. Kawakami M, et al. J Biosci Bioeng, 2014 Jun. PMID 24378667
  2. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Mukhopadhyay M, et al. Dev Cell, 2001 Sep. PMID 11702953
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dkk-1 regulates maxillary morphogenesis in chick embryos through Lhx8, Msx1 and Msx2 signals.
    Title: Inhibition of Wnt/β-catenin pathway by Dickkopf-1 [corrected] affects midfacial morphogenesis in chick embryo.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables co-receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor antagonist activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dickkopf-related protein 1
Names
dickkopf WNT signaling pathway inhibitor 1
dickkopf homolog 1

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10957318..10958457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040702954.2 → XP_040558888.1  dickkopf-related protein 1 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10828419..10829860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040674752.2 → XP_040530686.1  dickkopf-related protein 1 isoform X2

    Conserved Domains (1) summary
    pfam04706
    Location:63 → 115
    Dickkopf_N; Dickkopf N-terminal cysteine-rich region
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials