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CDH5 cadherin 5 [ Gallus gallus (chicken) ]

Gene ID: 374068, updated on 5-Sep-2025
Symbol
CDH5provided by CGNC
Full Name
cadherin 5provided by CGNC
Primary source
CGNC:3922
See related
Ensembl:ENSGALG00010007270
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
cadherin-5
Orthologs
human mouse all
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See CDH5 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (11164699..11194052, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (11509529..11538871, complement)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101749275 Neighboring gene brain expressed associated with NEDD4 1 Neighboring gene uncharacterized LOC121106555 Neighboring gene uncharacterized LOC124417142

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation. Mercado-Pimentel ME, et al. Dev Biol, 2007 Apr 1. PMID 17250821, Free PMC Article
  2. VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin. Gavard J, et al. Nat Cell Biol, 2006 Nov. PMID 17060906
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adherens junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of establishment of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasculature development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cadherin-5
Names
cadherin 5, type 2 (vascular endothelium)
cadherin 5, type 2, VE-cadherin (vascular endothelium)
cadherin 5, type 2, VE-cadherin (vascular epithelium)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204227.2 → NP_989558.2  cadherin-5 precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000248
    UniProtKB/Swiss-Prot
    F1P1Y9, Q8AYD0
    Related
    ENSGALP00010009604.1, ENSGALT00010017354.1
    Conserved Domains (1) summary
    cd11304
    Location:148 → 247
    Cadherin_repeat; Cadherin tandem repeat domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    11164699..11194052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046899376.1 → XP_046755332.1  cadherin-5 isoform X2

    UniProtKB/Swiss-Prot
    F1P1Y9, Q8AYD0

  2. XM_046899375.1 → XP_046755331.1  cadherin-5 isoform X1

    UniProtKB/Swiss-Prot
    F1P1Y9, Q8AYD0
    UniProtKB/TrEMBL
    A0A8V0XN44
    Related
    ENSGALP00010009606.1, ENSGALT00010017360.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    11509529..11538871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925342.1 → XP_046781298.1  cadherin-5 isoform X2

    UniProtKB/Swiss-Prot
    F1P1Y9, Q8AYD0

  2. XM_046925341.1 → XP_046781297.1  cadherin-5 isoform X1

    UniProtKB/Swiss-Prot
    F1P1Y9, Q8AYD0
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8AYD0.2 GenPept UniProtKB/Swiss-Prot:Q8AYD0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.