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TBX2 T-box transcription factor 2 [ Gallus gallus (chicken) ]

Gene ID: 373990, updated on 13-Apr-2026
Symbol
TBX2provided by CGNC
Full Name
T-box transcription factor 2provided by CGNC
Primary source
CGNC:16508
See related
Ensembl:ENSGALG00010029321
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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See TBX2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (8115353..8124715, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (7852185..7861563, complement)

Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107280 Neighboring gene uncharacterized LOC124417316 Neighboring gene T-box 4 Neighboring gene uncharacterized LOC772381 Neighboring gene uncharacterized LOC121107281 Neighboring gene WAS/WASL-interacting protein family member 1-like Neighboring gene BCAS3, microtubule associated cell migration factor Neighboring gene uncharacterized LOC121107285

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity. Logan M, et al. Development, 1998 Aug. PMID 9655805
  2. Tbx genes and limb identity in chick embryo development. Isaac A, et al. Development, 1998 May. PMID 9550719
  3. Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling. Suzuki T, et al. Dev Cell, 2004 Jan. PMID 14723846
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
T-box transcription factor TBX2
Names
T-Box protein 2
T-box 2

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    8115353..8124715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001235320.7 → XP_001235321.5  T-box transcription factor TBX2

    UniProtKB/TrEMBL
    A0A8V1AJI8
    Related
    ENSGALP00010043601.1, ENSGALT00010070910.1
    Conserved Domains (1) summary
    smart00425
    Location:96 → 282
    TBOX; Domain first found in the mice T locus (Brachyury) protein

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    7852185..7861563 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040687456.2 → XP_040543390.1  T-box transcription factor TBX2

    Conserved Domains (2) summary
    pfam12598
    Location:295 → 371
    TBX; T-box transcription factor
    cd20188
    Location:96 → 277
    T-box_TBX2_3-like; DNA-binding domain of T-box transcription factor 2 and 3, and related T-box proteins
Nucleotide Protein
Heading Accession and Version

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