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aifm1 apoptosis inducing factor mitochondrion associated 1 [ Danio rerio (zebrafish) ]

Gene ID: 373125, updated on 17-Nov-2020

Summary

Official Symbol
aifm1provided by ZNC
Official Full Name
apoptosis inducing factor mitochondrion associated 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030826-11
See related
Ensembl:ENSDARG00000058088
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
A; AIF; pdcd; pdcd8; zgc:91994
Orthologs

Genomic context

See aifm1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (22550614..22573724, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (22046814..22069932, complement)
103 previous assembly Zv9 (GCF_000002035.4) 5 NC_007116.5 (24333942..24357064, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L36A Neighboring gene glycine receptor, alpha 4b Neighboring gene tumor necrosis factor (ligand) superfamily, member 10 like 4 Neighboring gene caspase 22, apoptosis-related cysteine peptidase

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
apoptosis-inducing factor 1, mitochondrial
Names
programmed cell death 8 (apoptosis-inducing factor)
NP_956396.2
XP_005165182.1
XP_005165184.1
XP_009299566.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_200102.2NP_956396.2  apoptosis-inducing factor 1, mitochondrial

    See identical proteins and their annotated locations for NP_956396.2

    Status: PROVISIONAL

    Source sequence(s)
    BC084689
    UniProtKB/TrEMBL
    Q5XFY2
    Related
    ENSDARP00000075326.4, ENSDART00000080882.6
    Conserved Domains (3) summary
    pfam00070
    Location:304388
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:139449
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14721
    Location:467593
    AIF_C; Apoptosis-inducing factor, mitochondrion-associated, C-term

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    22550614..22573724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005165127.3XP_005165184.1  apoptosis-inducing factor 1, mitochondrial isoform X2

    Conserved Domains (3) summary
    pfam00070
    Location:431515
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:266576
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14721
    Location:594720
    AIF_C; Apoptosis-inducing factor, mitochondrion-associated, C-term
  2. XM_009301291.2XP_009299566.1  apoptosis-inducing factor 1, mitochondrial isoform X3

    Conserved Domains (3) summary
    pfam00070
    Location:312396
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:147457
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14721
    Location:475601
    AIF_C; Apoptosis-inducing factor, mitochondrion-associated, C-term
  3. XM_005165125.3XP_005165182.1  apoptosis-inducing factor 1, mitochondrial isoform X1

    UniProtKB/TrEMBL
    F1RBU0
    Related
    ENSDARP00000120028.1, ENSDART00000131889.3
    Conserved Domains (4) summary
    pfam00070
    Location:439523
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase
    pfam07992
    Location:274584
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
    pfam14721
    Location:602728
    AIF_C; Apoptosis-inducing factor, mitochondrion-associated, C-term
    pfam14962
    Location:56203
    AIF-MLS; Mitochondria Localization Sequence

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394573.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    65676..88735 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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