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hes6 hes family bHLH transcription factor 6 [ Danio rerio (zebrafish) ]

Gene ID: 373116, updated on 17-Nov-2020

Summary

Official Symbol
hes6provided by ZNC
Official Full Name
hes family bHLH transcription factor 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-030828-5
See related
Ensembl:ENSDARG00000019335
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
YF-30; her13.; her13.2
Orthologs

Genomic context

See hes6 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (48303165..48304696)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (48449001..48450532)
103 previous assembly Zv9 (GCF_000002035.4) 2 NC_007113.5 (48417337..48418868)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptor 55-like Neighboring gene lysophosphatidic acid receptor 5a Neighboring gene integral membrane protein 2Cb Neighboring gene period circadian clock 2 Neighboring gene uncharacterized LOC110437927

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of neurogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
somitogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription repressor complex IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
transcription cofactor HES-6
Names
hairy and enhancer of split 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_194400.2NP_919381.2  transcription cofactor HES-6

    See identical proteins and their annotated locations for NP_919381.2

    Status: PROVISIONAL

    Source sequence(s)
    BC065599
    UniProtKB/TrEMBL
    Q6P0J1
    Related
    ENSDARP00000021078.7, ENSDART00000023040.8
    Conserved Domains (2) summary
    cd00083
    Location:1875
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam07527
    Location:90128
    Hairy_orange; Hairy Orange

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    48303165..48304696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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