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CG10081 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37226, updated on 12-Aug-2026
Official Symbol
CG10081provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034441
Locus tag
Dmel_CG10081
See related
AllianceGenome:FB:FBgn0034441
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10081
Summary
Predicted to enable metalloexopeptidase activity. Predicted to be involved in proteolysis. Orthologous to human ERMP1 (endoplasmic reticulum metallopeptidase 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See CG10081 in Genome Data Viewer
Location:
56D2-56D3; 2-89 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19385923..19389318)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15273428..15276823)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Succinate dehydrogenase, subunit A (flavoprotein) Neighboring gene antisense RNA:CR45925 Neighboring gene crammer

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Seizure suppression by gain-of-function escargot mutations. Hekmat-Scafe DS, et al. Genetics, 2005 Mar. PMID 15654097, Free PMC Article
  2. The transcriptional diversity of 25 Drosophila cell lines. Cherbas L, et al. Genome Res, 2011 Feb. PMID 21177962, Free PMC Article
  3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
  4. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metalloexopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein
Names
CG10081-PA
CG10081-PB

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19385923..19389318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137574.3 → NP_611418.1  uncharacterized protein Dmel_CG10081, isoform A

    See identical proteins and their annotated locations for NP_611418.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZBK5, Q4V5E4
    Related
    FBpp0085712
    Conserved Domains (1) summary
    cd03875
    Location:72 → 379
    M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1

  2. NM_001274162.1 → NP_001261091.1  uncharacterized protein Dmel_CG10081, isoform B

    See identical proteins and their annotated locations for NP_001261091.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KG92
    Conserved Domains (1) summary
    cd03875
    Location:72 → 379
    M28_Fxna_like; M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4KG92 A0A0B4KG92
Q4V5E4 Q4V5E4

Gene LinkOut

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