Format

Send to:

Choose Destination

5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 37196, updated on 10-Jan-2019

Summary

Official Symbol
5-HT1Aprovided by FlyBase
Official Full Name
5-hydroxytryptamine (serotonin) receptor 1Aprovided by FlyBase
Primary source
FLYBASE:FBgn0004168
Locus tag
Dmel_CG16720
Gene type
protein coding
RNA name
5-hydroxytryptamine (serotonin) receptor 1A
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
5-HT-dro2A; 5-HT1a; 5-HT1ADro; 5-HT[1A]Dro; 5-HT[[1ADro]]; 5-HT[[1A]]; 5-HT[[1A]]DRO; 5HT-1A; 5HT-dro2A; 5HT-drp[[2A]]; 5HT-R2A; 5HT1a; 5HT1A; 5htdro2a; 5HT[[1ADro]]; CG16720; d5-HT1A; Dm5-HT[[1A]]; Dm5HTdro2A; Dmel\CG16720; DRO2A; HT1A

Genomic context

See 5-HT1A in Genome Data Viewer
Location:
56B2-56B5; 2-88 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.18 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19067155..19121958)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14954660..15009463)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 56a Neighboring gene uncharacterized protein Neighboring gene brother of tout-velu

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

  • Homologs of the 5-HT1A gene: The 5-HT1A gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
G protein-coupled amine receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled serotonin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
G protein-coupled serotonin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled serotonin receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
G protein-coupled serotonin receptor activity TAS
Traceable Author Statement
more info
PubMed 
Gi/o-coupled serotonin receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
neurotransmitter receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
5-hydroxytryptamine (serotonin) receptor 1A
Names
5-HT1A-PB
CG16720-PB
serotonin receptor 1A
serotonin receptor 2A
serotonin-receptor-2A

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    19067155..19121958
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_166322.2NP_725849.1  5-hydroxytryptamine (serotonin) receptor 1A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725849.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28285
    Related
    FBpp0085761, FBtr0086577
    Conserved Domains (1) summary
    pfam00001
    Location:243413
    7tm_1; 7 transmembrane receptor (rhodopsin family)
Support Center