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Bap55 Brahma associated protein 55kD [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36956, updated on 30-Jun-2026
Official Symbol
Bap55provided by FlyBase
Official Full Name
Brahma associated protein 55kDprovided by FlyBase
Primary source
FLYBASE:FBgn0025716
Locus tag
Dmel_CG6546
See related
AllianceGenome:FB:FBgn0025716
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Arp4; ARP4; Baf53; BAF53; BAF55; BAP47; bap55; BAP55; CG6546; Dmel\CG6546
Summary
Predicted to enable chromatin binding activity. Involved in DNA repair-dependent chromatin remodeling; dendrite guidance; and regulation of DNA-templated transcription. Part of NuA4 histone acetyltransferase complex and brahma complex. Is expressed in several structures, including adult head; central brain primordium; embryonic/larval midgut; embryonic/larval midgut primordium; and ganglia. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76. Orthologous to several human genes including ACTL6B (actin like 6B). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See Bap55 in Genome Data Viewer
Location:
54B7-54B7; 2-82 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17429353..17430963, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13316858..13318468, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene lethal (2) k01209 Neighboring gene uncharacterized protein Neighboring gene Methylthioadenosine phosphorylase Neighboring gene Lethal hybrid rescue Neighboring gene Egg-derived tyrosine phosphatase Neighboring gene uncharacterized protein

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. GBAF, a small BAF sub-complex with big implications: a systematic review. Innis SM, et al. Epigenetics Chromatin, 2020 Nov 3. PMID 33143733, Free PMC Article
  2. Noncanonical action of circadian clock genes controls winter diapause entry via the NuA4/TIP60 complex in Harmonia axyridis. Gao Q, et al. Proc Natl Acad Sci U S A, 2025 Jul 15. PMID 40638091, Free PMC Article
  3. Unconventional roles of chromatin remodelers and long non-coding RNAs in cell division. Prozzillo Y, et al. Cell Mol Life Sci, 2023 Nov 20. PMID 37982870, Free PMC Article
  4. The Swi/Snf family nucleosome-remodeling complexes and transcriptional control. Sudarsanam P, et al. Trends Genet, 2000 Aug. PMID 10904263
  5. Cis-by-Trans regulatory divergence causes the asymmetric lethal effects of an ancestral hybrid incompatibility gene. Maheshwari S, et al. PLoS Genet, 2012. PMID 22457639, Free PMC Article

See all (129) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Preferred Names
brahma associated protein 55kD
Names
BRM-associated protein 55
Bap55-PA
CG6546-PA
brahma associated protein 55 kD
brahma associated protein of 55kD

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17429353..17430963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137365.4 → NP_611209.1  brahma associated protein 55kD

    See identical proteins and their annotated locations for NP_611209.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAS6, Q7K012
    Related
    FBpp0086115
    Conserved Domains (1) summary
    pfam00022
    Location:13 → 425
    Actin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K012 Q7K012

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