U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG4927 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36852, updated on 16-Jun-2026
Official Symbol
CG4927provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0034139
Locus tag
Dmel_CG4927
See related
AllianceGenome:FB:FBgn0034139
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
cSP42; Dmel\CG4927; SP42
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in spermatozoon. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See CG4927 in Genome Data Viewer
Location:
53C8-53C8; 2-80 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16572082..16574154)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12459587..12461659)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Dopamine transporter Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein S15 Neighboring gene Limostatin Neighboring gene antisense RNA:CR44375 Neighboring gene Cyclin-dependent kinase 4

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila. Shan T, et al. Sci Adv, 2023 Dec 22. PMID 38117884, Free PMC Article
  2. Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster. Huylmans AK, et al. G3 (Bethesda), 2014 Sep 22. PMID 25246242, Free PMC Article
  3. Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E(spl)/Hes genes. Housden BE, et al. PLoS Genet, 2013. PMID 23300480, Free PMC Article
  4. The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity. Kwon SY, et al. Dev Biol, 2008 Apr 15. PMID 18334252
  5. Changes in Neuronal Signaling and Cell Stress Response Pathways are Associated with a Multigenic Response of Drosophila melanogaster to DDT Selection. Seong KM, et al. Genome Biol Evol, 2017 Dec 1. PMID 29211847, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Preferred Names
uncharacterized protein
Names
CG4927-PC
NP_001033953.1

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    16572082..16574154
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001038864.2 → NP_001033953.1  uncharacterized protein Dmel_CG4927

    See identical proteins and their annotated locations for NP_001033953.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAH9, Q4V3U8
    Conserved Domains (2) summary
    smart00020
    Location:105 → 355
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:105 → 358
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V3U8 Q4V3U8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools