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ktn1 kinectin 1 [ Danio rerio (zebrafish) ]

Gene ID: 368207, updated on 9-Sep-2025
Official Symbol
ktn1provided by ZNC
Official Full Name
kinectin 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030408-4
See related
Ensembl:ENSDARG00000032802 AllianceGenome:ZFIN:ZDB-GENE-030408-4
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb213; wu:fi20e02; wu:fi27f06
Summary
Predicted to enable kinesin binding activity. Predicted to act upstream of or within microtubule-based movement and protein transport. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including alar plate midbrain region; eye; liver; midbrain; and musculature system. Orthologous to human KTN1 (kinectin 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
human mouse all
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Location:
chromosome: 17
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2025_04 current GRCz12tu (GCF_049306965.1) 17 NC_133192.1 (48912347..48988119)
RS_2024_08 previous assembly GRCz11 (GCF_000002035.6) 17 NC_007128.7 (43926475..44002251)

Chromosome 17 - NC_133192.1Genomic Context describing neighboring genes Neighboring gene amylase alpha 2A-like 1 Neighboring gene mutS homolog 4 Neighboring gene uncharacterized LOC141378413 Neighboring gene uncharacterized LOC141378412 Neighboring gene uncharacterized LOC100535512 Neighboring gene pellino E3 ubiquitin protein ligase family member 2 Neighboring gene uncharacterized LOC141378415

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Related articles in PubMed

  1. RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish. Frese KS, et al. J Cell Sci, 2015 Aug 15. PMID 26116573, Free PMC Article
  2. Genome wide analysis reveals Zic3 interaction with distal regulatory elements of stage specific developmental genes in zebrafish. Winata CL, et al. PLoS Genet, 2013 Oct. PMID 24204288, Free PMC Article
  3. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables kinesin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule-based movement IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
kinectin

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001309329.1 → NP_001296258.1  kinectin isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    DY545513, EB897878, EB943723, EH489828, JBMGRA010000017
    UniProtKB/TrEMBL
    A0A8M1P1K0, E7F049
    Related
    ENSDARP00000107134.2, ENSDART00000121550.4
    Conserved Domains (1) summary
    pfam10174
    Location:462 → 1193
    Cast; RIM-binding protein of the cytomatrix active zone

  2. NM_200081.2 → NP_956375.2  kinectin isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    DY545513, EB897878, EB943723, EH489828, JBMGRA010000017
    UniProtKB/TrEMBL
    A0A8N7UZY7, F1QJA1
    Related
    ENSDARP00000041446.6, ENSDART00000041447.7
    Conserved Domains (1) summary
    COG1196
    Location:384 → 1207
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RefSeqs of Annotated Genomes: GCF_049306965.1-RS_2025_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz12tu Primary Assembly

Genomic

  1. NC_133192.1 Reference GRCz12tu Primary Assembly

    Range
    48912347..48988119
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005158886.3 → XP_005158943.1  kinectin isoform X2

    UniProtKB/TrEMBL
    A0A8M2B5B8
    Related
    ENSDARP00000005691.10, ENSDART00000017376.10
    Conserved Domains (1) summary
    COG1196
    Location:384 → 1206
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_005158887.4 → XP_005158944.1  kinectin isoform X5

    UniProtKB/TrEMBL
    A0A8M2B5C3
    Conserved Domains (1) summary
    COG1196
    Location:384 → 1182
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_005158885.4 → XP_005158942.1  kinectin isoform X1

    UniProtKB/TrEMBL
    A0A8M2B5E8
    Conserved Domains (2) summary
    pfam10174
    Location:461 → 1192
    Cast; RIM-binding protein of the cytomatrix active zone
    pfam16031
    Location:220 → 265
    TonB_N; TonB N-terminal region

  4. XM_073926997.1 → XP_073783098.1  kinectin isoform X3

  5. XM_073926998.1 → XP_073783099.1  kinectin isoform X4

  6. XM_073926999.1 → XP_073783100.1  kinectin isoform X6

RNA

  1. XR_012392640.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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