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Rorc RAR-related orphan receptor C [ Rattus norvegicus (Norway rat) ]

Gene ID: 368158, updated on 22-Nov-2020

Summary

Official Symbol
Rorcprovided by RGD
Official Full Name
RAR-related orphan receptor Cprovided by RGD
Primary source
RGD:1595785
See related
Ensembl:ENSRNOG00000020836
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 399.9), Liver (RPKM 124.0) and 5 other tissues See more
Orthologs

Genomic context

See Rorc in Genome Data Viewer
Location:
2q34
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (195612471..195636797)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene thioesterase superfamily member 5 Neighboring gene C2 calcium-dependent domain containing 4D Neighboring gene leucine rich repeat and Ig domain containing 4 Neighboring gene tudor and KH domain containing Neighboring gene cytochrome c, somatic-like Neighboring gene ornithine decarboxylase antizyme 3

Genomic regions, transcripts, and products

Genomic Sequence:
NC_005101.4 Chromosome 2 Reference Rnor_6.0 Primary Assembly

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC189525

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
ligand-activated transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
nuclear receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 
oxysterol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxysterol binding ISO
Inferred from Sequence Orthology
more info
 
sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription coactivator binding ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
Peyer's patch development ISO
Inferred from Sequence Orthology
more info
 
T cell differentiation in thymus ISO
Inferred from Sequence Orthology
more info
 
T-helper 17 cell differentiation ISO
Inferred from Sequence Orthology
more info
 
T-helper cell differentiation ISO
Inferred from Sequence Orthology
more info
 
adipose tissue development ISO
Inferred from Sequence Orthology
more info
 
alpha-beta T cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cellular response to sterol ISO
Inferred from Sequence Orthology
more info
 
circadian regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
circadian rhythm IEP
Inferred from Expression Pattern
more info
PubMed 
intracellular receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
lymph node development ISO
Inferred from Sequence Orthology
more info
 
mucosa-associated lymphoid tissue development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of thymocyte apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of circadian rhythm ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
regulation of fat cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of gamma-delta T cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of glucose metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of steroid metabolic process ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
xenobiotic metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear body IEA
Inferred from Electronic Annotation
more info
 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
nuclear receptor ROR-gamma
Names
RAR-related orphan receptor gamma

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    195612471..195636797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591313.1XP_017446802.1  nuclear receptor ROR-gamma isoform X3

  2. XM_006232926.3XP_006232988.2  nuclear receptor ROR-gamma isoform X1

    Conserved Domains (2) summary
    cd06939
    Location:258496
    NR_LBD_ROR_like; The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily
    cd06968
    Location:24118
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
  3. XM_008761339.1XP_008759561.1  nuclear receptor ROR-gamma isoform X2

    UniProtKB/TrEMBL
    A0A0G2QC01
    Related
    ENSRNOP00000058884.3, ENSRNOT00000067042.3
    Conserved Domains (2) summary
    cd06939
    Location:237475
    NR_LBD_ROR_like; The ligand binding domain of Retinoid-related orphan receptors, of the nuclear receptor superfamily
    cd06968
    Location:497
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
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