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CngA Cyclic nucleotide-gated ion channel subunit A [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36806, updated on 6-Apr-2017
Official Symbol
CngAprovided by FlyBase
Official Full Name
Cyclic nucleotide-gated ion channel subunit Aprovided by FlyBase
Primary source
FLYBASE:FBgn0261612
Locus tag
Dmel_CG42701
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG15709; CG42701; CG7779; cng; Cng; CNG; dCNCalpha; dmCNGA; DmCNGA; DmCNGC; Dmel\CG42701
Old locus tag
Dmel_CG15709; Dmel_CG7779
Location:
53A2-53A2
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (16243145..16259805, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (12130650..12147310, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene krimper Neighboring gene CG15708 gene product from transcript CG15708-RA Neighboring gene CG7773 gene product from transcript CG7773-RA Neighboring gene capsuleen

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
intracellular cyclic nucleotide activated cation channel activity IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
cGMP-mediated signaling IDA
Inferred from Direct Assay
more info
PubMed 
cGMP-mediated signaling TAS
Traceable Author Statement
more info
PubMed 
cation transport IDA
Inferred from Direct Assay
more info
PubMed 
regulation of membrane potential IBA
Inferred from Biological aspect of Ancestor
more info
 
response to hypoxia IGI
Inferred from Genetic Interaction
more info
PubMed 
response to hypoxia IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
intracellular cyclic nucleotide activated cation channel complex IDA
Inferred from Direct Assay
more info
PubMed 
intracellular cyclic nucleotide activated cation channel complex NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
CG42701 gene product from transcript CG42701-RB
Names
CG42701-PA
CG42701-PB
CNG channel alpha subunit
CNG-channel
CngA-PA
CngA-PB
Cyclic-nucleotide-gated ion channel protein
cyclic nucleotide-gated ion channel subunit A

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    16243145..16259805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202031.2NP_001188960.1  cyclic nucleotide-gated ion channel subunit A, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188960.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JCU4
    Related
    FBpp0292051, FBtr0302925
    Conserved Domains (5) summary
    COG0664
    Location:598722
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    cd00038
    Location:604717
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:309529
    Ion_trans; Ion transport protein
    pfam07885
    Location:477527
    Ion_trans_2; Ion channel
    pfam16526
    Location:720791
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
  2. NM_057768.3NP_477116.1  cyclic nucleotide-gated ion channel subunit A, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477116.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24278
    Related
    FBpp0292050, FBtr0302924
    Conserved Domains (5) summary
    COG0664
    Location:423547
    Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
    cd00038
    Location:429542
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
    pfam00520
    Location:134354
    Ion_trans; Ion transport protein
    pfam07885
    Location:302352
    Ion_trans_2; Ion channel
    pfam16526
    Location:545616
    CLZ; C-terminal leucine zipper domain of cyclic nucleotide-gated channels
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