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Alg9 ALG9, alpha-1,2-mannosyltransferase [ Rattus norvegicus (Norway rat) ]

Gene ID: 367083, updated on 24-Jul-2025
Official Symbol
Alg9provided by RGD
Official Full Name
ALG9, alpha-1,2-mannosyltransferaseprovided by RGD
Primary source
RGD:1311272
See related
Ensembl:ENSRNOG00000010877 AllianceGenome:RGD:1311272
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Dibd1
Summary
Predicted to enable dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity and dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Il. Orthologous to human ALG9 (ALG9 alpha-1,2-mannosyltransferase). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Adrenal (RPKM 52.2), Kidney (RPKM 36.5) and 9 other tissues See more
Orthologs
human mouse all
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See Alg9 in Genome Data Viewer
Location:
8q23
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (60013429..60085159)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (51117057..51188790)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (55202140..55265478)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene 2 Neighboring gene cilia and flagella associated protein 68 Neighboring gene ferredoxin-fold anticodon binding domain containing 1 Neighboring gene uncharacterized LOC134480165 Neighboring gene 60S ribosomal protein L27a-like Neighboring gene protein phosphatase 2 scaffold subunit A beta Neighboring gene salt-inducible kinase 2

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables alpha-1,2-mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in dolichol-linked oligosaccharide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein N-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
alpha-1,2-mannosyltransferase ALG9
Names
asparagine-linked glycosylation 9 homolog (S. cerevisiae, alpha- 1,2-mannosyltransferase)
asparagine-linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase)
asparagine-linked glycosylation 9 protein
asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog
disrupted in bipolar affective disorder 1
NP_001381277.1
NP_001381278.1
XP_038937793.1
XP_038937794.1
XP_038937795.1
XP_038937796.1
XP_038937797.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001394348.1 → NP_001381277.1  alpha-1,2-mannosyltransferase ALG9 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I6GCZ5, D3ZCW5
    Related
    ENSRNOP00000085516.1, ENSRNOT00000098102.2
    Conserved Domains (1) summary
    pfam03901
    Location:68 → 490
    Glyco_transf_22; Alg9-like mannosyltransferase family

  2. NM_001394349.1 → NP_001381278.1  alpha-1,2-mannosyltransferase ALG9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8I5Y6Z5, A0A8I6GCZ5
    Related
    ENSRNOP00000078122.1, ENSRNOT00000115652.2
    Conserved Domains (1) summary
    pfam03901
    Location:25 → 447
    Glyco_transf_22; Alg9-like mannosyltransferase family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    60013429..60085159
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081868.2 → XP_038937796.1  alpha-1,2-mannosyltransferase ALG9 isoform X1

    Conserved Domains (1) summary
    cl21590
    Location:51 → 377
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  2. XM_039081865.2 → XP_038937793.1  alpha-1,2-mannosyltransferase ALG9 isoform X1

    Conserved Domains (1) summary
    cl21590
    Location:51 → 377
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  3. XM_039081866.2 → XP_038937794.1  alpha-1,2-mannosyltransferase ALG9 isoform X1

    Conserved Domains (1) summary
    cl21590
    Location:51 → 377
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  4. XM_039081869.2 → XP_038937797.1  alpha-1,2-mannosyltransferase ALG9 isoform X2

    Conserved Domains (1) summary
    cl21590
    Location:1 → 311
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

  5. XM_039081867.2 → XP_038937795.1  alpha-1,2-mannosyltransferase ALG9 isoform X1

    Conserved Domains (1) summary
    cl21590
    Location:51 → 377
    PMT_2; Dolichyl-phosphate-mannose-protein mannosyltransferase

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001109000.1: Suppressed sequence

    Description
    NM_001109000.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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