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Patl2 PAT1 homolog 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 366176, updated on 5-Mar-2024

Summary

Official Symbol
Patl2provided by RGD
Official Full Name
PAT1 homolog 2provided by RGD
Primary source
RGD:1307887
See related
Ensembl:ENSRNOG00000017061 AllianceGenome:RGD:1307887
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1307887
Summary
Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Predicted to be located in cytoplasm and nucleus. Predicted to be active in P-body. Orthologous to human PATL2 (PAT1 homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 4.7), Testes (RPKM 3.1) and 5 other tissues See more
Orthologs
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Genomic context

Location:
3q35
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (129526563..129543267, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (109072958..109087425, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (114065814..114075404, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene CTD small phosphatase like 2 Neighboring gene uncharacterized LOC134486142 Neighboring gene eukaryotic translation initiation factor 3, subunit J Neighboring gene SPG11 vesicle trafficking associated, spatacsin Neighboring gene beta-2 microglobulin Neighboring gene tripartite motif-containing 69

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in P-body assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of cytoplasmic mRNA processing body assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in P-body ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein PAT1 homolog 2
Names
protein associated with topoisomerase II homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    129526563..129543267 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284981.1XP_063141051.1  protein PAT1 homolog 2