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B3galt1 Beta-1,3-galactosyltransferase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 366064, updated on 5-Sep-2025
Official Symbol
B3galt1provided by RGD
Official Full Name
Beta-1,3-galactosyltransferase 1provided by RGD
Primary source
RGD:1311898
See related
Ensembl:ENSRNOG00000007625 AllianceGenome:RGD:1311898
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity. Predicted to be involved in galactosylceramide biosynthetic process; lipid glycosylation; and protein O-linked glycosylation. Predicted to act upstream of or within oligosaccharide biosynthetic process. Predicted to be active in Golgi membrane. Orthologous to human B3GALT1 (beta-1,3-galactosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Liver (RPKM 124.2), Brain (RPKM 30.5) and 1 other tissue See more
Orthologs
human mouse all
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See B3galt1 in Genome Data Viewer
Location:
3q21
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (72661410..73234447)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (52253413..52826508)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (53699409..54269612)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC134486373 Neighboring gene xin actin-binding repeat containing 2 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134486374 Neighboring gene uncharacterized LOC100911723 Neighboring gene serine threonine kinase 39 Neighboring gene dnaJ homolog subfamily C member 8-like

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. Amado M, et al. J Biol Chem, 1998 May 22. PMID 9582303
  2. Genomic cloning and expression of three murine UDP-galactose: beta-N-acetylglucosamine beta1,3-galactosyltransferase genes. Hennet T, et al. J Biol Chem, 1998 Jan 2. PMID 9417047
  3. Proteomics characterization of abundant Golgi membrane proteins. Bell AW, et al. J Biol Chem, 2001 Feb 16. PMID 11042173
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in galactosylceramide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within oligosaccharide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in oligosaccharide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
beta-1,3-galactosyltransferase 1
Names
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
NP_001102424.1
XP_017447431.1
XP_017447434.1
XP_017447435.1
XP_017447437.1
XP_038961517.1
XP_038961518.1
XP_063140336.1
XP_063140337.1
XP_063140338.1
XP_063140339.1
XP_063140341.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108954.2 → NP_001102424.1  beta-1,3-galactosyltransferase 1

    See identical proteins and their annotated locations for NP_001102424.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  2. NM_001434404.1 → NP_001421333.1  beta-1,3-galactosyltransferase 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8

  3. NM_001434405.1 → NP_001421334.1  beta-1,3-galactosyltransferase 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003
    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8

RNA

  1. NR_197780.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  2. NR_197781.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

  3. NR_197782.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    72661410..73234447
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017591942.3 → XP_017447431.1  beta-1,3-galactosyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Related
    ENSRNOP00000010018.4, ENSRNOT00000010018.6
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  2. XM_039105589.2 → XP_038961517.1  beta-1,3-galactosyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  3. XM_017591945.3 → XP_017447434.1  beta-1,3-galactosyltransferase 1 isoform X2

    Related
    ENSRNOP00000106104.1, ENSRNOT00000138050.1
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  4. XM_063284271.1 → XP_063140341.1  beta-1,3-galactosyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Related
    ENSRNOP00000102829.1, ENSRNOT00000172616.1

  5. XM_063284269.1 → XP_063140339.1  beta-1,3-galactosyltransferase 1 isoform X1

  6. XM_063284268.1 → XP_063140338.1  beta-1,3-galactosyltransferase 1 isoform X1

  7. XM_063284266.1 → XP_063140336.1  beta-1,3-galactosyltransferase 1 isoform X1

  8. XM_063284267.1 → XP_063140337.1  beta-1,3-galactosyltransferase 1 isoform X1

  9. XM_017591946.3 → XP_017447435.1  beta-1,3-galactosyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Related
    ENSRNOP00000104470.1, ENSRNOT00000170985.1
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  10. XM_039105590.2 → XP_038961518.1  beta-1,3-galactosyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A6HLY9, D3ZPD8
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase

  11. XM_017591948.3 → XP_017447437.1  beta-1,3-galactosyltransferase 1 isoform X2

    Related
    ENSRNOP00000086959.1, ENSRNOT00000097712.2
    Conserved Domains (1) summary
    pfam01762
    Location:92 → 279
    Galactosyl_T; Galactosyltransferase
Nucleotide Protein Strain
Heading Accession and Version

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