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Cyb5r2 cytochrome b5 reductase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365345, updated on 12-Aug-2018

Summary

Official Symbol
Cyb5r2provided by RGD
Official Full Name
cytochrome b5 reductase 2provided by RGD
Primary source
RGD:1308421
See related
Ensembl:ENSRNOG00000019751
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308421
Expression
Biased expression in Heart (RPKM 58.5), Muscle (RPKM 37.5) and 9 other tissues See more
Orthologs

Genomic context

See Cyb5r2 in Genome Data Viewer
Location:
1q33
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (171971424..171981586, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (178964826..178979214, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene elongation factor 1-alpha 1-like Neighboring gene synaptotagmin 9 Neighboring gene olfactomedin-like 1 Neighboring gene PPFIA binding protein 2 Neighboring gene LRRGT00141 Neighboring gene ovochymase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
FAD binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytochrome-b5 reductase activity, acting on NAD(P)H IEA
Inferred from Electronic Annotation
more info
 
cytochrome-b5 reductase activity, acting on NAD(P)H ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process ISO
Inferred from Sequence Orthology
more info
 
sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
NADH-cytochrome b5 reductase 2
Names
b5R.2
NP_001014266.1
XP_008758000.1
XP_017444969.1
XP_017444970.1
XP_017444971.1
XP_017444972.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014244.1NP_001014266.1  NADH-cytochrome b5 reductase 2

    See identical proteins and their annotated locations for NP_001014266.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079235
    UniProtKB/Swiss-Prot
    Q6AY12
    Related
    ENSRNOP00000026744.6, ENSRNOT00000026744.7
    Conserved Domains (2) summary
    cd06183
    Location:20276
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
    PTZ00319
    Location:13276
    PTZ00319; NADH-cytochrome B5 reductase; Provisional

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    171971424..171981586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008759778.2XP_008758000.1  NADH-cytochrome b5 reductase 2 isoform X2

    See identical proteins and their annotated locations for XP_008758000.1

    Conserved Domains (1) summary
    cd06183
    Location:20159
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
  2. XM_017589480.1XP_017444969.1  NADH-cytochrome b5 reductase 2 isoform X1

  3. XM_017589481.1XP_017444970.1  NADH-cytochrome b5 reductase 2 isoform X1

  4. XM_017589482.1XP_017444971.1  NADH-cytochrome b5 reductase 2 isoform X2

    Conserved Domains (1) summary
    cd06183
    Location:20159
    cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...
  5. XM_017589483.1XP_017444972.1  NADH-cytochrome b5 reductase 2 isoform X3

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    159561210..159569444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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