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Tpte2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364629, updated on 21-Jul-2018

Summary

Official Symbol
Tpte2provided by RGD
Official Full Name
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2provided by RGD
Primary source
RGD:1305825
See related
Ensembl:ENSRNOG00000024837
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tpte
Expression
Restricted expression toward (RPKM 30.3) See more

Genomic context

See Tpte2 in Genome Data Viewer
Location:
16q12.5
Exon count:
32
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (74552859..74662194, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 16 NC_005115.3 (74195701..74298014, complement)

Chromosome 16 - NC_005115.4Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 19 Neighboring gene mitochondrial ribosomal protein S31 Neighboring gene solute carrier family 25 member 15 Neighboring gene activated RNA polymerase II transcriptional coactivator p15-like Neighboring gene thrombospondin type 1 domain containing 1 Neighboring gene vacuolar protein sorting 36 homolog

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2
Names
transmembrane phosphatase with tensin homology
NP_001102347.1
XP_017455689.1
XP_017455690.1
XP_017455691.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108877.1NP_001102347.1  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2

    See identical proteins and their annotated locations for NP_001102347.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473970
    UniProtKB/TrEMBL
    D4ADC8
    Related
    ENSRNOP00000029743.5, ENSRNOT00000034670.5
    Conserved Domains (3) summary
    smart00404
    Location:429481
    PTPc_motif; Protein tyrosine phosphatase, catalytic domain motif
    COG2453
    Location:411528
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    pfam10409
    Location:532666
    PTEN_C2; C2 domain of PTEN tumour-suppressor protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005115.4 Reference Rnor_6.0 Primary Assembly

    Range
    74552859..74662194 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600201.1XP_017455690.1  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 isoform X2

  2. XM_017600202.1XP_017455691.1  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 isoform X2

  3. XM_017600200.1XP_017455689.1  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase TPTE2 isoform X1

RNA

  1. XR_001841543.1 RNA Sequence

Alternate Rn_Celera

Genomic

  1. AC_000084.1 Alternate Rn_Celera

    Range
    67548914..67642237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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