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Bcas3 BCAS3, microtubule associated cell migration factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 363662, updated on 18-Apr-2019

Summary

Official Symbol
Bcas3provided by RGD
Official Full Name
BCAS3, microtubule associated cell migration factorprovided by RGD
Primary source
RGD:1560788
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1560788
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Lung (RPKM 116.5), Kidney (RPKM 83.7) and 9 other tissues See more
Orthologs

Genomic context

See Bcas3 in Genome Data Viewer
Location:
10q26
Exon count:
18
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (72756548..73271851) , (72951303..73015309)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (72660671..73177317)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene similar to Chromodomain-helicase-DNA-binding protein 1 (CHD-1) Neighboring gene amyloid beta precursor protein binding protein 2 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1D Neighboring gene uncharacterized LOC102554092 Neighboring gene T-box 2 Neighboring gene T-box 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
acetyltransferase activator activity ISO
Inferred from Sequence Orthology
more info
PubMed 
beta-tubulin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
chromatin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
histone acetyltransferase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
histone binding ISO
Inferred from Sequence Orthology
more info
PubMed 
molecular_function ND
No biological Data available
more info
 
nuclear hormone receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
Golgi organization ISO
Inferred from Sequence Orthology
more info
PubMed 
activation of GTPase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
biological_process ND
No biological Data available
more info
 
cellular response to estrogen stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
microtubule organizing center organization ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of focal adhesion assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of actin cytoskeleton reorganization ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of catalytic activity ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of endothelial cell migration ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of filopodium assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of intracellular protein transport ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of establishment of cell polarity ISO
Inferred from Sequence Orthology
more info
PubMed 
tube formation ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cell leading edge ISO
Inferred from Sequence Orthology
more info
PubMed 
cell periphery ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular_component ND
No biological Data available
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasmic microtubule ISO
Inferred from Sequence Orthology
more info
PubMed 
intermediate filament cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
transcriptionally active chromatin ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
breast carcinoma amplified sequence 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001173430.1NP_001166901.1  breast carcinoma amplified sequence 3

    Status: VALIDATED

    Source sequence(s)
    AAHX01065280, AAHX01065281, AAHX01065282, AAHX01065283, AAHX01065284, AAHX01065285, AAHX01065286, AAHX01065289
    Conserved Domains (2) summary
    pfam12490
    Location:581753
    BCAS3; Breast carcinoma amplified sequence 3
    cl02567
    Location:344449
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    72756548..73271851
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    69140091..69598397
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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