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Cd109 CD109 molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 363104, updated on 18-Apr-2019

Summary

Official Symbol
Cd109provided by RGD
Official Full Name
CD109 moleculeprovided by RGD
Primary source
RGD:1311287
See related
Ensembl:ENSRNOG00000025332
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Testes (RPKM 41.9), Lung (RPKM 30.1) and 9 other tissues See more
Orthologs

Genomic context

See Cd109 in Genome Data Viewer
Location:
8q31
Exon count:
33
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (85951420..86065411)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (85500667..85615070)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549445 Neighboring gene solute carrier family 17 member 5 Neighboring gene similar to RIKEN cDNA 2900055D03 Neighboring gene similar to nuclease sensitive element binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta binding IEA
Inferred from Electronic Annotation
more info
 
transforming growth factor beta binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
extracellular space IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    85951420..86065411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003750546.4XP_003750594.1  CD109 antigen

    See identical proteins and their annotated locations for XP_003750594.1

    UniProtKB/TrEMBL
    D4A447
    Related
    ENSRNOP00000030391.4, ENSRNOT00000037665.5
    Conserved Domains (7) summary
    COG2373
    Location:1221019
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd02897
    Location:9091195
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:695784
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:129220
    A2M_N; MG2 domain
    pfam07677
    Location:13111395
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:9611197
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:472598
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    79200276..79310457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003754439.3XP_003754487.1  CD109 antigen

    See identical proteins and their annotated locations for XP_003754487.1

    UniProtKB/TrEMBL
    D4A447
    Conserved Domains (7) summary
    COG2373
    Location:1221019
    YfaS; Uncharacterized conserved protein YfaS, alpha-2-macroglobulin family [General function prediction only]
    cd02897
    Location:9091195
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:695784
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:129220
    A2M_N; MG2 domain
    pfam07677
    Location:13111395
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:9611197
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:472598
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001108771.1: Suppressed sequence

    Description
    NM_001108771.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: CD109 (GeneID:135228).
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