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Pole4 DNA polymerase epsilon 4, accessory subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 362385, updated on 2-Oct-2018

Summary

Official Symbol
Pole4provided by RGD
Official Full Name
DNA polymerase epsilon 4, accessory subunitprovided by RGD
Primary source
RGD:1307793
See related
Ensembl:ENSRNOG00000006102
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Heart (RPKM 230.0), Kidney (RPKM 152.1) and 9 other tissues See more
Orthologs

Genomic context

See Pole4 in Genome Data Viewer
Location:
4q34
Exon count:
4
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (113491644..113497455, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (178170534..178176366, complement)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27a, pseudogene 17 Neighboring gene tachykinin receptor 1 Neighboring gene uncharacterized LOC102547728 Neighboring gene hexokinase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
histone H3 acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone H3 acetylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Ada2/Gcn5/Ada3 transcription activator complex ISO
Inferred from Sequence Orthology
more info
 
cellular_component ND
No biological Data available
more info
 
epsilon DNA polymerase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
epsilon DNA polymerase complex ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
DNA polymerase epsilon subunit 4
Names
DNA-directed DNA polymerase epsilon 4
polymerase (DNA) epsilon 4, accessory subunit
polymerase (DNA-directed), epsilon 4 (p12 subunit)
polymerase (DNA-directed), epsilon 4, accessory subunit
NP_001102104.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108634.1NP_001102104.1  DNA polymerase epsilon subunit 4

    See identical proteins and their annotated locations for NP_001102104.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473957
    UniProtKB/TrEMBL
    D3Z9P5
    Related
    ENSRNOP00000058863.1, ENSRNOT00000067314.1
    Conserved Domains (1) summary
    cl23735
    Location:41104
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    113491644..113497455 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    104161837..104167648 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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