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Elovl7 ELOVL fatty acid elongase 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361895, updated on 3-Jun-2026
Official Symbol
Elovl7provided by RGD
Official Full Name
ELOVL fatty acid elongase 7provided by RGD
Primary source
RGD:1310560
See related
Ensembl:ENSRNOG00000010450 AllianceGenome:RGD:1310560
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable fatty acid elongase activity. Predicted to be involved in fatty acid biosynthetic process and sphingolipid biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human ELOVL7 (ELOVL fatty acid elongase 7). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Kidney (RPKM 248.6), Adrenal (RPKM 248.4) and 8 other tissues See more
Orthologs
all
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See Elovl7 in Genome Data Viewer
Location:
2q14
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (41522695..41592021)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (39789229..39858579)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (40373211..40386643, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L29, pseudogene 23 Neighboring gene egl-9 family hypoxia-inducible factor 1, pseudogene 5 Neighboring gene uncharacterized LOC134485833 Neighboring gene uncharacterized LOC108350211 Neighboring gene DEP domain containing 1B Neighboring gene phosphodiesterase 4D Neighboring gene uncharacterized LOC120101083

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism. Tamura K, et al. Cancer Res, 2009 Oct 15. PMID 19826053
  2. ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis. Ohno Y, et al. Proc Natl Acad Sci U S A, 2010 Oct 26. PMID 20937905, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables fatty acid elongase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fatty acid elongase activity IEA
Inferred from Electronic Annotation
more info
  
enables fatty acid elongase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid elongation, monounsaturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid elongation, monounsaturated fatty acid IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid elongation, polyunsaturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid elongation, polyunsaturated fatty acid IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid elongation, polyunsaturated fatty acid ISO
Inferred from Sequence Orthology
more info
  
involved_in fatty acid elongation, saturated fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fatty acid elongation, saturated fatty acid IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid elongation, saturated fatty acid ISO
Inferred from Sequence Orthology
more info
  
involved_in lipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in long-chain fatty-acyl-CoA biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in sphingolipid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in unsaturated fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in very long-chain fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in very long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in very long-chain fatty acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
very long chain fatty acid elongase 7
Names
3-keto acyl-CoA synthase Elovl7
ELOVL FA elongase 7
elongation of very long chain fatty acids protein 7
very long chain 3-ketoacyl-CoA synthase 7
very long chain 3-oxoacyl-CoA synthase 7
NP_001178773.1
XP_038958484.1
XP_038958485.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191844.1 → NP_001178773.1  very long chain fatty acid elongase 7

    See identical proteins and their annotated locations for NP_001178773.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/Swiss-Prot
    D4ADY9
    Conserved Domains (1) summary
    pfam01151
    Location:30 → 269
    ELO; GNS1/SUR4 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    41522695..41592021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102556.2 → XP_038958484.1  very long chain fatty acid elongase 7 isoform X1

    UniProtKB/Swiss-Prot
    D4ADY9
    Related
    ENSRNOP00000014074.5, ENSRNOT00000014074.7
    Conserved Domains (1) summary
    pfam01151
    Location:30 → 269
    ELO; GNS1/SUR4 family

  2. XM_039102557.2 → XP_038958485.1  very long chain fatty acid elongase 7 isoform X2

    UniProtKB/TrEMBL
    A0A0A0MXW4
    Conserved Domains (1) summary
    pfam01151
    Location:1 → 182
    ELO; GNS1/SUR4 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D4ADY9.1 GenPept UniProtKB/Swiss-Prot:D4ADY9

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