Ppp1r18 protein phosphatase 1, regulatory subunit 18 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ppp1r18provided by RGD
Official Full Name: protein phosphatase 1, regulatory subunit 18provided by RGD
Primary source: RGD:1309543
See related: Ensembl:ENSRNOG00000071251 AllianceGenome:RGD:1309543
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Kiaa1949; RGD1309543
Summary: Predicted to enable actin binding activity and phosphatase binding activity. Predicted to be located in cytoplasm. Orthologous to human PPP1R18 (protein phosphatase 1 regulatory subunit 18). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Spleen (RPKM 92.8), Lung (RPKM 89.6) and 9 other tissues See more
Orthologs: all
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Genomic context

Location:: 20p12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (2882370..2892329, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (2877567..2887526, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (3372412..3397351, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

AI236751 (e-PCR)
- UniSTS:250627

RH139928 (e-PCR)
- UniSTS:222012

AI450394 (e-PCR)
- UniSTS:160655

D20Rat71 (e-PCR), detects polymorphism
- UniSTS:227303

General protein information

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Preferred Names: phostensin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.