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Ms4a6a membrane spanning 4-domains A6A [ Rattus norvegicus (Norway rat) ]

Gene ID: 361735, updated on 10-Feb-2026
Official Symbol
Ms4a6aprovided by RGD
Official Full Name
membrane spanning 4-domains A6Aprovided by RGD
Primary source
RGD:1305800
See related
Ensembl:ENSRNOG00000020991 AllianceGenome:RGD:1305800
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ms4a11
Summary
Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane and trans-Golgi network. Orthologous to several human genes including MS4A6A (membrane spanning 4-domains A6A). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Spleen (RPKM 160.7), Liver (RPKM 64.4) and 7 other tissues See more
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See Ms4a6a in Genome Data Viewer
Location:
1q43
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (217826261..217839606, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (208401465..208414831, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (227919284..227932637, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551452 Neighboring gene membrane-spanning 4-domains, subfamily A, member 4C, pseudogene 1 Neighboring gene membrane-spanning 4-domains, subfamily A, member 6B-like 2 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene membrane spanning 4-domains A2

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in trans-Golgi network ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
membrane-spanning 4-domains subfamily A member 6D
Names
membrane-spanning 4-domains, subfamily A, member 11
membrane-spanning 4-domains, subfamily A, member 6A

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001408758.1 → NP_001395687.1  membrane-spanning 4-domains subfamily A member 6D

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    F1LZT4
    Related
    ENSRNOP00000034434.7, ENSRNOT00000033795.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    217826261..217839606 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039101356.2 → XP_038957284.1  membrane-spanning 4-domains subfamily A member 6D isoform X2

    Conserved Domains (1) summary
    pfam04103
    Location:1 → 156
    CD20; CD20-like family

  2. XM_039101355.2 → XP_038957283.1  membrane-spanning 4-domains subfamily A member 6D isoform X1

    UniProtKB/TrEMBL
    F1LZT4
    Conserved Domains (1) summary
    pfam04103
    Location:47 → 209
    CD20; CD20-like family
Nucleotide Protein Strain
Heading Accession and Version

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