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Tead1 TEA domain transcription factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361630, updated on 19-Apr-2019

Summary

Official Symbol
Tead1provided by RGD
Official Full Name
TEA domain transcription factor 1provided by RGD
Primary source
RGD:1549742
See related
Ensembl:ENSRNOG00000015488
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
TEF-1
Expression
Biased expression in Heart (RPKM 148.6), Muscle (RPKM 145.1) and 9 other tissues See more
Orthologs

Genomic context

See Tead1 in Genome Data Viewer
Location:
1q33
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (177495500..177714795)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (184473090..184690968)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108349616 Neighboring gene parvin, alpha Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 pseudogene Neighboring gene Ras association domain family member 10 Neighboring gene uncharacterized LOC102547978

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription activator activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
PubMed 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
DNA-binding transcription factor activity, RNA polymerase II-specific ISO
Inferred from Sequence Orthology
more info
PubMed 
RNA polymerase II proximal promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
RNA polymerase II transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
PubMed 
sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription coactivator binding ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription regulator recruiting activity ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular response to retinoic acid ISO
Inferred from Sequence Orthology
more info
PubMed 
embryonic heart tube morphogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
heart development ISO
Inferred from Sequence Orthology
more info
PubMed 
hippo signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hippo signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
lateral mesoderm development ISO
Inferred from Sequence Orthology
more info
PubMed 
notochord development ISO
Inferred from Sequence Orthology
more info
PubMed 
paraxial mesoderm development ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of pri-miRNA transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of stem cell population maintenance ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
protein-containing complex assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of gene expression ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
PubMed 
transition between fast and slow fiber ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
TEAD-1-YAP complex ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor complex ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
transcriptional enhancer factor TEF-1
Names
TEA domain family member 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001198589.1NP_001185518.1  transcriptional enhancer factor TEF-1

    See identical proteins and their annotated locations for NP_001185518.1

    Status: VALIDATED

    Source sequence(s)
    AABR07005039, AABR07005040, AY529195
    UniProtKB/TrEMBL
    F1M7P3, Q6QQU2
    Related
    ENSRNOP00000021020.3, ENSRNOT00000021020.4
    Conserved Domains (1) summary
    smart00426
    Location:1582
    TEA; TEA domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    177495500..177714795
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230052.2XP_006230114.1  transcriptional enhancer factor TEF-1 isoform X1

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  2. XM_006230053.2XP_006230115.1  transcriptional enhancer factor TEF-1 isoform X2

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  3. XM_006230055.2XP_006230117.1  transcriptional enhancer factor TEF-1 isoform X4

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  4. XM_006230057.2XP_006230119.1  transcriptional enhancer factor TEF-1 isoform X6

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  5. XM_006230054.2XP_006230116.1  transcriptional enhancer factor TEF-1 isoform X3

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  6. XM_006230056.2XP_006230118.1  transcriptional enhancer factor TEF-1 isoform X5

    Conserved Domains (1) summary
    smart00426
    Location:210277
    TEA; TEA domain
  7. XM_006230058.2XP_006230120.1  transcriptional enhancer factor TEF-1 isoform X7

    Conserved Domains (1) summary
    smart00426
    Location:210269
    TEA; TEA domain
  8. XM_006230059.2XP_006230121.1  transcriptional enhancer factor TEF-1 isoform X10

    UniProtKB/TrEMBL
    A0A0G2K2N3
    Related
    ENSRNOP00000072311.1, ENSRNOT00000090042.1
    Conserved Domains (1) summary
    smart00426
    Location:1582
    TEA; TEA domain
  9. XM_008759768.1XP_008757990.1  transcriptional enhancer factor TEF-1 isoform X9

    Conserved Domains (1) summary
    smart00426
    Location:53120
    TEA; TEA domain
  10. XM_008759767.2XP_008757989.1  transcriptional enhancer factor TEF-1 isoform X8

    Conserved Domains (1) summary
    smart00426
    Location:56123
    TEA; TEA domain

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    164664658..164874391
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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