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Fam168a family with sequence similarity 168, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 361614, updated on 3-Jun-2026
Official Symbol
Fam168aprovided by RGD
Official Full Name
family with sequence similarity 168, member Aprovided by RGD
Primary source
RGD:1308929
See related
Ensembl:ENSRNOG00000018873 AllianceGenome:RGD:1308929
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308929
Summary
Predicted to be involved in positive regulation of base-excision repair. Orthologous to human FAM168A (family with sequence similarity 168 member A). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Brain (RPKM 214.3), Adrenal (RPKM 85.1) and 9 other tissues See more
Orthologs
all
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See Fam168a in Genome Data Viewer
Location:
1q32
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (164469447..164615542)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (155057352..155203439)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (165723278..165880612)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA4 Neighboring gene RAB6A, member RAS oncogene family Neighboring gene pleckstrin homology domain containing B1 Neighboring gene RELT, TNF receptor Neighboring gene Rho guanine nucleotide exchange factor 17 Neighboring gene microRNA 3102

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. TCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cells. Liu X, et al. Mol Cell Biochem, 2015 Jan. PMID 25260657
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in positive regulation of base-excision repair IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of base-excision repair IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of base-excision repair ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
protein FAM168A

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108494.1 → NP_001101964.1  protein FAM168A

    See identical proteins and their annotated locations for NP_001101964.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473956
    UniProtKB/TrEMBL
    A0A8I6A572, A6I6R4
    Conserved Domains (1) summary
    pfam14944
    Location:1 → 244
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    164469447..164615542
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006229773.5 → XP_006229835.1  protein FAM168A isoform X4

    See identical proteins and their annotated locations for XP_006229835.1

    UniProtKB/TrEMBL
    A0A8I5ZR57, A0A8I6A572, A6I6R5
    Related
    ENSRNOP00000081214.2, ENSRNOT00000097710.2
    Conserved Domains (1) summary
    pfam14944
    Location:1 → 235
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  2. XM_039082504.2 → XP_038938432.1  protein FAM168A isoform X3

    UniProtKB/TrEMBL
    A0A8I6A572, A6I6R4
    Related
    ENSRNOP00000087972.1, ENSRNOT00000106607.2
    Conserved Domains (1) summary
    pfam14944
    Location:1 → 244
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  3. XM_039082510.2 → XP_038938438.1  protein FAM168A isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZR57, A0A8I6A572, A6I6R5
    Conserved Domains (1) summary
    pfam14944
    Location:1 → 235
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  4. XM_017589376.3 → XP_017444865.1  protein FAM168A isoform X1

    UniProtKB/TrEMBL
    A0A8I6A572, A0ABK0M3I0
    Related
    ENSRNOP00000109680.1, ENSRNOT00000164813.1
    Conserved Domains (1) summary
    pfam14944
    Location:12 → 255
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  5. XM_039082512.2 → XP_038938440.1  protein FAM168A isoform X5

    Conserved Domains (1) summary
    pfam14944
    Location:12 → 204
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1

  6. XM_017589377.3 → XP_017444866.1  protein FAM168A isoform X2

    UniProtKB/TrEMBL
    A0A8I6A572, D3ZHW1
    Related
    ENSRNOP00000025827.6, ENSRNOT00000025827.7
    Conserved Domains (1) summary
    pfam14944
    Location:12 → 246
    TCRP1; Tongue Cancer Chemotherapy Resistant Protein 1
Nucleotide Protein Strain
Heading Accession and Version

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