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Mtrf1l mitochondrial translation release factor 1 like [ Rattus norvegicus (Norway rat) ]

Gene ID: 361473, updated on 6-Jul-2026
Official Symbol
Mtrf1lprovided by RGD
Official Full Name
mitochondrial translation release factor 1 likeprovided by RGD
Primary source
RGD:1598312
See related
Ensembl:ENSRNOG00000018773 AllianceGenome:RGD:1598312
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable translation release factor activity, codon specific. Predicted to be involved in mitochondrial translational termination. Predicted to be active in mitochondrion. Orthologous to human MTRF1L (mitochondrial translation release factor 1 like). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Thymus (RPKM 103.8), Kidney (RPKM 81.7) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Mtrf1l in Genome Data Viewer
Location:
1q11
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (44614162..44626367, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (42208553..42221020, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097707 Neighboring gene small nucleolar RNA U2-19 Neighboring gene small nucleolar RNA U2-30 Neighboring gene F-box protein 5 Neighboring gene regulator of G-protein signaling 17 Neighboring gene uncharacterized LOC134484991

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC116100

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables translation release factor activity IEA
Inferred from Electronic Annotation
more info
  
enables translation release factor activity ISO
Inferred from Sequence Orthology
more info
  
enables translation release factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables translation release factor activity, codon specific IEA
Inferred from Electronic Annotation
more info
  
enables translation release factor activity, codon specific ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translational termination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial translational termination IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial translational termination ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial translational termination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translational termination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
peptide chain release factor 1-like, mitochondrial
Names
mitochondrial translational release factor 1-like

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025723.3 → NP_001020894.1  peptide chain release factor 1-like, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001020894.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/Swiss-Prot
    Q4V7E5
    UniProtKB/TrEMBL
    A0A8L2QF03
    Related
    ENSRNOP00000025398.6, ENSRNOT00000025398.9
    Conserved Domains (3) summary
    COG1186
    Location:123 → 355
    PrfB; Protein chain release factor B [Translation, ribosomal structure and biogenesis]
    pfam00472
    Location:224 → 329
    RF-1; RF-1 domain
    pfam03462
    Location:57 → 214
    PCRF; PCRF domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    44614162..44626367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081235.2 → XP_038937163.1  peptide chain release factor 1-like, mitochondrial isoform X1

    Conserved Domains (1) summary
    cl40670
    Location:90 → 279
    PCRF; PCRF domain

  2. XM_063266098.1 → XP_063122168.1  peptide chain release factor 1-like, mitochondrial isoform X3

  3. XM_063266088.1 → XP_063122158.1  peptide chain release factor 1-like, mitochondrial isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V7E5.1 GenPept UniProtKB/Swiss-Prot:Q4V7E5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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