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Asb5 ankyrin repeat and SOCS box-containing 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361187, updated on 21-Jul-2018

Summary

Official Symbol
Asb5provided by RGD
Official Full Name
ankyrin repeat and SOCS box-containing 5provided by RGD
Primary source
RGD:1565973
See related
Ensembl:ENSRNOG00000042630
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Muscle (RPKM 160.4), Heart (RPKM 11.9) and 2 other tissues See more
Orthologs

Genomic context

See Asb5 in Genome Data Viewer
Location:
16p11
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (39985233..40050663, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 16 NC_005115.3 (39760399..39826806, complement)

Chromosome 16 - NC_005115.4Genomic Context describing neighboring genes Neighboring gene WD repeat domain 17 Neighboring gene spermatogenesis associated 4 Neighboring gene signal peptidase complex subunit 3 Neighboring gene vascular endothelial growth factor C

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Clone Names

  • MGC114420

Gene Ontology Provided by RGD

Process Evidence Code Pubs
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ankyrin repeat and SOCS box protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044247.1NP_001037712.1  ankyrin repeat and SOCS box protein 5

    See identical proteins and their annotated locations for NP_001037712.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098935
    UniProtKB/TrEMBL
    Q4KLY9
    Related
    ENSRNOP00000061114.2, ENSRNOT00000066639.3
    Conserved Domains (5) summary
    cd00204
    Location:71188
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:273314
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:74165
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:218267
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:71100
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005115.4 Reference Rnor_6.0 Primary Assembly

    Range
    39985233..40050663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017600191.1XP_017455680.1  ankyrin repeat and SOCS box protein 5 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:71188
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:288329
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:74165
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:71100
    ANK; ANK repeat [structural motif]
  2. XM_017600190.1XP_017455679.1  ankyrin repeat and SOCS box protein 5 isoform X1

    Conserved Domains (4) summary
    cd00204
    Location:71188
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:288329
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:74165
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:71100
    ANK; ANK repeat [structural motif]
  3. XM_008771247.2XP_008769469.1  ankyrin repeat and SOCS box protein 5 isoform X1

    See identical proteins and their annotated locations for XP_008769469.1

    Conserved Domains (4) summary
    cd00204
    Location:71188
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:288329
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:74165
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:71100
    ANK; ANK repeat [structural motif]
  4. XM_006253100.3XP_006253162.1  ankyrin repeat and SOCS box protein 5 isoform X2

    Related
    ENSRNOP00000074476.1, ENSRNOT00000089665.1
    Conserved Domains (4) summary
    cd00204
    Location:48165
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:265306
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:51142
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:4877
    ANK; ANK repeat [structural motif]
  5. XM_008771248.2XP_008769470.1  ankyrin repeat and SOCS box protein 5 isoform X3

    Conserved Domains (4) summary
    cd00204
    Location:26143
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03724
    Location:243284
    SOCS_ASB5; SOCS (suppressors of cytokine signaling) box of ASB5-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ASB5 has been implicated in the initiation of arteriogenesis. The general function of the SOCS ...
    pfam12796
    Location:29120
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:2655
    ANK; ANK repeat [structural motif]

Alternate Rn_Celera

Genomic

  1. AC_000084.1 Alternate Rn_Celera

    Range
    35364045..35403104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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