U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Alg11 ALG11, alpha-1,2-mannosyltransferase [ Rattus norvegicus (Norway rat) ]

Gene ID: 361174, updated on 24-Jul-2025
Official Symbol
Alg11provided by RGD
Official Full Name
ALG11, alpha-1,2-mannosyltransferaseprovided by RGD
Primary source
RGD:1564725
See related
Ensembl:ENSRNOG00000012841 AllianceGenome:RGD:1564725
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564725
Summary
Predicted to enable GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ip. Orthologous to human ALG11 (ALG11 alpha-1,2-mannosyltransferase). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Liver (RPKM 79.2), Kidney (RPKM 60.3) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See Alg11 in Genome Data Viewer
Location:
16q12.5
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (76642979..76654052, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (69940540..69951617, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (74854007..74866096, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene NIMA-related kinase 3 Neighboring gene NIMA-related kinase 5 Neighboring gene ATPase copper transporting beta Neighboring gene coiled-coil domain containing 70

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in dolichol-linked oligosaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in dolichol-linked oligosaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in dolichol-linked oligosaccharide biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein N-linked glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Names
asparagine-linked glycosylation 11 homolog (S. cerevisiae, alpha-1,2-mannosyltransferase)
asparagine-linked glycosylation 11 homolog (yeast, alpha-1,2-mannosyltransferase)
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog
asparagine-linked glycosylation protein 11 homolog
NP_001101871.1
XP_006253416.1
XP_006253417.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108401.1 → NP_001101871.1  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

    See identical proteins and their annotated locations for NP_001101871.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473970
    UniProtKB/TrEMBL
    A6IW87, A6IW88, D3ZCQ2
    Related
    ENSRNOP00000017163.4, ENSRNOT00000017164.6
    Conserved Domains (1) summary
    cd03806
    Location:63 → 480
    GT4_ALG11-like; alpha-1,2-mannosyltransferase ALG11 and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    76642979..76654052 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006253354.4 → XP_006253416.1  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform X1

    See identical proteins and their annotated locations for XP_006253416.1

    UniProtKB/TrEMBL
    A6IW87
    Conserved Domains (1) summary
    cd03806
    Location:1 → 418
    GT4_ALG11-like; alpha-1,2-mannosyltransferase ALG11 and similar proteins

  2. XM_006253355.5 → XP_006253417.1  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform X1

    See identical proteins and their annotated locations for XP_006253417.1

    UniProtKB/TrEMBL
    A6IW87
    Conserved Domains (1) summary
    cd03806
    Location:1 → 418
    GT4_ALG11-like; alpha-1,2-mannosyltransferase ALG11 and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools