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Envelope surface glycoprotein gp120
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env
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Tandem affinity purification and mass spectrometry analysis identify interleukin enhancer binding factor 3 (ILF3, NF90), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
|
Gag-Pol
|
gag-pol
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Tandem affinity purification and mass spectrometry analysis identify interleukin enhancer binding factor 3 (ILF3, NF90), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
|
Nef
|
nef
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Tandem affinity purification and mass spectrometry analysis identify interleukin enhancer binding factor 3 (ILF3, NF90), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
|
Pr55(Gag)
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gag
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Tandem affinity purification and mass spectrometry analysis identify interleukin enhancer binding factor 3 (ILF3, NF90), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells |
PubMed
|
|
Rev
|
rev
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HIV-1 Rev interacting protein, interleukin enhancer binding factor 3 (ILF3), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with ILF3 is increased by RRE |
PubMed
|
|
rev
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NF90 inhibits HIV-1 Rev-dependent activity by interfering with the RNA export function of Rev |
PubMed
|
|
rev
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NF90-RRE-RNA interaction alters HIV-1 Rev subcellular localization |
PubMed
|
|
rev
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Three specific domains (residues 89-123, 405-593, and 594-670) of NF90 promote Rev-RRE mediated nuclear export of Gag mRNA, which is dependent on CRM1 function |
PubMed
|
|
rev
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The C-terminal 67 amino acids (604-671) of NF90 interact with HIV-1 Rev |
PubMed
|
|
Tat
|
tat
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NF90ctv-TAR RNA interaction shows significant inhibition of Tat-transactivation of the HIV-1 LTR in cells expressing NF90ctv, as well as changes in histone H3 methylation of HIV chromatin |
PubMed
|
|
tat
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The C-terminal variant of nuclear factor 90 (NF90ctv) with strong affinity for HIV-1 TAR RNA, competes with Tat/TAR interaction in vitro |
PubMed
|
|
Vpr
|
vpr
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A stable-isotope labeling by amino acids in cell culture coupled with mass spectrometry-based proteomics identifies downregulation of interleukin enhancer binding factor 3 (ILF3, NF90) expression by HIV-1 Vpr in Vpr transduced macrophages |
PubMed
|
|
capsid
|
gag
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Expression of NF90 drastically reduces the amount of p24 expression, suggesting inhibition of HIV-1 particle production |
PubMed
|