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Hr3 Hormone receptor 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36073, updated on 28-Aug-2019

Summary

Official Symbol
Hr3provided by FlyBase
Official Full Name
Hormone receptor 3provided by FlyBase
Primary source
FLYBASE:FBgn0000448
Locus tag
Dmel_CG33183
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
12.6; 2.4; CG11823; CG12208; CG33183; D; dhr3; dHR3; Dhr3; DHR3; Dmel\CG33183; DmHr3; DmRORalpha; HR3; hr46; Hr46; l(2)46CFi; l(2)k09242; NR1F4

Genomic context

See Hr3 in Genome Data Viewer
Location:
46F5-46F7; 2-62 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10203995..10237348, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6091500..6124853, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene KCNQ potassium channel Neighboring gene mulet Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46322 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45265 Neighboring gene Histidine decarboxylase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

  • Homologs of the Hr3 gene: The Hr3 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, C.elegans, and frog.

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
RNA polymerase II regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
nuclear receptor activity NAS
Non-traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
hormone receptor 3
Names
CG33183-PA
CG33183-PC
CG33183-PD
CG33183-PF
CG33183-PH
CG33183-PI
Hr3-PA
Hr3-PC
Hr3-PD
Hr3-PF
Hr3-PH
Hr3-PI
complementation group D
hormone receptor-like 46
hormone receptor-like in 46
NP_001334718.1
  • non-AUG (ACG) translation initiation

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10203995..10237348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001347757.1NP_001334718.1  hormone receptor 3, isoform I [Drosophila melanogaster]

    Status: REVIEWED

    Related
    FBpp0402891, FBtr0452140
  2. NM_001259307.3NP_001246236.1  hormone receptor 3, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246236.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P31396
    UniProtKB/TrEMBL
    H1UUN3
    Related
    FBpp0297438, FBtr0306345
    Conserved Domains (2) summary
    cd06968
    Location:44138
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
    cl11397
    Location:236478
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  3. NM_001103786.2NP_001097256.1  hormone receptor 3, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097256.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8DY91
    Related
    FBpp0111711, FBtr0112799
    Conserved Domains (2) summary
    cd06968
    Location:15109
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
    cl11397
    Location:205447
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  4. NM_176121.3NP_788301.1  hormone receptor 3, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788301.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z858
    Related
    FBpp0087454, FBtr0088366
    Conserved Domains (2) summary
    cd06968
    Location:253347
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
    cl11397
    Location:443685
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  5. NM_176123.5NP_788303.1  hormone receptor 3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788303.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P31396
    UniProtKB/TrEMBL
    H1UUN3
    Related
    FBpp0087456, FBtr0088368
    Conserved Domains (2) summary
    cd06968
    Location:44138
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
    cl11397
    Location:236478
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  6. NM_001273925.2NP_001260854.1  hormone receptor 3, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260854.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4KEJ3
    Related
    FBpp0303459, FBtr0330609
    Conserved Domains (2) summary
    cd06968
    Location:44138
    NR_DBD_ROR; DNA-binding domain of Retinoid-related orphan receptors (RORs) is composed of two C4-type zinc fingers
    cl11397
    Location:236478
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
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