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Nt5c3b 5'-nucleotidase, cytosolic IIIB [ Rattus norvegicus (Norway rat) ]

Gene ID: 360629, updated on 5-Jan-2022

Summary

Official Symbol
Nt5c3bprovided by RGD
Official Full Name
5'-nucleotidase, cytosolic IIIBprovided by RGD
Primary source
RGD:1359229
See related
Ensembl:ENSRNOG00000016475
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nt5c3l
Summary
Predicted to enable 5'-nucleotidase activity; magnesium ion binding activity; and nucleotide binding activity. Predicted to be involved in dephosphorylation and nucleotide metabolic process. Predicted to be active in cytoplasm. Orthologous to human NT5C3B (5'-nucleotidase, cytosolic IIIB). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Testes (RPKM 108.1), Adrenal (RPKM 91.8) and 9 other tissues See more
Orthologs
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Genomic context

See Nt5c3b in Genome Data Viewer
Location:
10q31
Exon count:
12
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (85358483..85376340, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (88338700..88356538, complement)

Chromosome 10 - NC_051345.1Genomic Context describing neighboring genes Neighboring gene prolyl 3-hydroxylase family member 4 Neighboring gene FKBP prolyl isomerase 10 Neighboring gene kelch-like family member 10 Neighboring gene kelch-like family member 11

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC93839

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NOT enables 5'-nucleotidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 5'-nucleotidase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
7-methylguanosine phosphate-specific 5'-nucleotidase
Names
5'-nucleotidase, cytosolic III-like
7-methylguanosine nucleotidase
N(7)-methylguanylate 5'-phosphatase
cN-III-like protein
cytosolic 5'-nucleotidase 3B
cytosolic 5'-nucleotidase III-like protein
cytosolic 5-nucleotidase III-like protein-like
NP_001007724.2
XP_008766306.1
XP_017452886.1
XP_038942331.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007723.2NP_001007724.2  7-methylguanosine phosphate-specific 5'-nucleotidase

    See identical proteins and their annotated locations for NP_001007724.2

    Status: VALIDATED

    Source sequence(s)
    AW527524, BC078963
    UniProtKB/Swiss-Prot
    Q6AYP7
    Related
    ENSRNOP00000022430.3, ENSRNOT00000022430.7
    Conserved Domains (1) summary
    pfam05822
    Location:44289
    UMPH-1; Pyrimidine 5'-nucleotidase (UMPH-1)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051345.1 Reference mRatBN7.2 Primary Assembly

    Range
    85358483..85376340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008768084.3XP_008766306.1  7-methylguanosine phosphate-specific 5'-nucleotidase isoform X2

    Conserved Domains (1) summary
    pfam05822
    Location:44256
    UMPH-1; Pyrimidine 5'-nucleotidase (UMPH-1)
  2. XM_039086403.1XP_038942331.1  7-methylguanosine phosphate-specific 5'-nucleotidase isoform X3

    Conserved Domains (1) summary
    pfam05822
    Location:10222
    UMPH-1; Pyrimidine 5'-nucleotidase (UMPH-1)
  3. XM_017597397.2XP_017452886.1  7-methylguanosine phosphate-specific 5'-nucleotidase isoform X1

    UniProtKB/Swiss-Prot
    Q6AYP7
    Conserved Domains (1) summary
    pfam05822
    Location:44289
    UMPH-1; Pyrimidine 5'-nucleotidase (UMPH-1)
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