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14-3-3zeta [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36059, updated on 12-Aug-2018

Summary

Official Symbol
14-3-3zetaprovided by FlyBase
Primary source
FLYBASE:FBgn0004907
Locus tag
Dmel_CG17870
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
14-3-3; 14-3-3 zeta; 14-3-3-Leo; 14-3-3-zeta; 14-3-3leo; 14-3-3z; 14-3-3ZETA; 2G1; 4-3-3 zeta; 5.11; 549; BEST:GH05075; CG17870; D14-3-3; d14-3-3zeta; D14-3-3zeta; Dmel\CG17870; K; l(2)07103; l(2)46CFe; l(2)46Ee; leo; Leo; LEO; par-5; Par-5; PAR-5; PAR5

Genomic context

See 14-3-3zeta in Genome Data Viewer
Location:
46E6-46E8; 2-62 cM
Exon count:
12
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10099677..10109687)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5987182..5997192)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene sugar transporter 4 Neighboring gene Ribosomal protein LP0-like Neighboring gene Jun-related antigen Neighboring gene Phosphofructokinase Neighboring gene dampened

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
protein kinase C inhibitor activity NAS
Non-traceable Author Statement
more info
PubMed 
transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasmic sequestering of transcription factor IMP
Inferred from Mutant Phenotype
more info
PubMed 
germarium-derived oocyte fate determination IGI
Inferred from Genetic Interaction
more info
PubMed 
learning or memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
learning or memory NAS
Non-traceable Author Statement
more info
PubMed 
mitotic cell cycle, embryonic IMP
Inferred from Mutant Phenotype
more info
PubMed 
olfactory learning NAS
Non-traceable Author Statement
more info
PubMed 
oocyte microtubule cytoskeleton polarization IGI
Inferred from Genetic Interaction
more info
PubMed 
positive regulation of Ras protein signal transduction HGI PubMed 
positive regulation of hippo signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
protein folding IDA
Inferred from Direct Assay
more info
PubMed 
protein folding IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein stabilization IDA
Inferred from Direct Assay
more info
PubMed 
protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
thermosensory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
14-3-3zeta
Names
14-3-3zeta-PA
14-3-3zeta-PB
14-3-3zeta-PC
14-3-3zeta-PD
14-3-3zeta-PE
14-3-3zeta-PF
14-3-3zeta-PG
14-3-3zeta-PH
14-3-3zeta-PI
14-3-3zeta-PJ
14-3-3zeta-PK
14-3-3zeta-PL
CG17870-PA
CG17870-PB
CG17870-PC
CG17870-PD
CG17870-PE
CG17870-PF
CG17870-PG
CG17870-PH
CG17870-PI
CG17870-PJ
CG17870-PK
CG17870-PL
D14 3 3 protein
Leonardo-13-3-3
complementation group K
leonardo
leonardo 14-3-3

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10099677..10109687
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165740.3NP_724884.1  14-3-3zeta, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724884.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    UniProtKB/TrEMBL
    A0A0B4KEH0
    Related
    FBpp0087503.1, FBtr0088415
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  2. NM_165742.2NP_724886.1  14-3-3zeta, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724886.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0087500.1, FBtr0088412
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  3. NM_206070.2NP_995792.1  14-3-3zeta, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_995792.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0089337.1, FBtr0088418
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  4. NM_165744.3NP_724888.2  14-3-3zeta, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724888.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0087504.1, FBtr0088416
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  5. NM_165745.3NP_724889.2  14-3-3zeta, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724889.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0087505.1, FBtr0088417
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  6. NM_057537.4NP_476885.2  14-3-3zeta, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_476885.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    UniProtKB/TrEMBL
    A0A0B4KEH0
    Related
    FBpp0087502.1, FBtr0088414
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  7. NM_165743.3NP_724887.2  14-3-3zeta, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724887.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0089338.1, FBtr0088419
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  8. NM_001014515.2NP_001014515.1  14-3-3zeta, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014515.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    UniProtKB/TrEMBL
    A0A0B4KEH0
    Related
    FBpp0099540.1, FBtr0100183
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  9. NM_165741.3NP_724885.1  14-3-3zeta, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724885.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0087501.1, FBtr0088413
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  10. NM_001014516.2NP_001014516.1  14-3-3zeta, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014516.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    Related
    FBpp0099539.1, FBtr0100182
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  11. NM_001273916.1NP_001260845.1  14-3-3zeta, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260845.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    UniProtKB/TrEMBL
    A0A0B4KEH0
    Related
    FBpp0305136.1, FBtr0332916
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
  12. NM_001273917.1NP_001260846.1  14-3-3zeta, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260846.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29310
    UniProtKB/TrEMBL
    A0A0B4KEH0
    Related
    FBpp0305137.1, FBtr0332917
    Conserved Domains (1) summary
    cl02098
    Location:5234
    14-3-3; 14-3-3 domain
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