eIF3j eukaryotic translation initiation factor 3 subunit j [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: eIF3jprovided by FlyBase
Official Full Name: eukaryotic translation initiation factor 3 subunit jprovided by FlyBase
Primary source: FLYBASE:FBgn0027619
Locus tag: Dmel_CG12131
See related: AllianceGenome:FB:FBgn0027619
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 5.3; Adam; CG12131; Dmel\CG12131; E; eIF3-S1; l(2)46Cf; l(2)46CFd; l(2)k13906; Q7K550_DROME
Summary: Enables translation initiation factor activity. Involved in regulation of translational initiation. Part of eukaryotic translation initiation factor 3 complex. Is expressed in several structures, including Malpighian tubule primordium; anterior endoderm; embryonic/larval midgut primordium; gut section; and somatic trunk mesoderm derivative. Orthologous to human EIF3J (eukaryotic translation initiation factor 3 subunit J). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (9968929..9970897)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (5856434..5858402)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

eIF3j inhibits translation of a subset of circular RNAs in eukaryotic cells.
Title: eIF3j inhibits translation of a subset of circular RNAs in eukaryotic cells.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables translation initiation factor activity	IDA Inferred from Direct Assay more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of translational initiation	IDA Inferred from Direct Assay more info	PubMed
involved_in translational initiation	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex	IDA Inferred from Direct Assay more info	PubMed
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: CG12131-PA; CG12131-PB; adam; complementation group E; eIF3j-PA; eIF3j-PB

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The following sections contain reference sequences that belong to a specific genome build. Explain