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PRAC2 PRAC2 small nuclear protein [ Homo sapiens (human) ]

Gene ID: 360205, updated on 23-Nov-2021

Summary

Official Symbol
PRAC2provided by HGNC
Official Full Name
PRAC2 small nuclear proteinprovided by HGNC
Primary source
HGNC:HGNC:30143
See related
Ensembl:ENSG00000229637 MIM:610787
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HOXBAS5; C17orf93; HOXB-AS5; HOXB13-AS1; NCRNA00253
Summary
This gene is highly expressed in prostate, rectum, colon, and testis. This gene may produce a non-coding RNA or may encode a short protein that might localize to the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Expression
Biased expression in prostate (RPKM 2.7), colon (RPKM 1.1) and 1 other tissue See more
Orthologs
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Genomic context

See PRAC2 in Genome Data Viewer
Location:
17q21.32
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (48720802..48724758)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46800547..46802120)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2086 Neighboring gene ribosomal protein L9 pseudogene 28 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene 2 Neighboring gene PRAC1 small nuclear protein Neighboring gene microRNA 3185 Neighboring gene homeobox B13 Neighboring gene uncharacterized LOC105371811

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative protein PRAC2
Names
HOXB cluster antisense RNA 5
prostate cancer susceptibility candidate 2
prostate, rectum and colon 2
prostate, rectum and colon expressed gene 2 protein
prostate, rectum and colon expressed gene protein 2
putative protein PRCA2
small nuclear protein PRAC2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001282275.2NP_001269204.1  putative protein PRAC2 isoform b

    See identical proteins and their annotated locations for NP_001269204.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus, compared to isoform a.
    Source sequence(s)
    AF532777, AI201489, BX106051
    Consensus CDS
    CCDS74100.1
    UniProtKB/Swiss-Prot
    D3DTV9
    Related
    ENSP00000481367.1, ENST00000422730.4
  2. NM_001282276.1NP_001269205.1  putative protein PRAC2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (a).
    Source sequence(s)
    AI201489, AI762586, BX106051
    Consensus CDS
    CCDS74099.1
    UniProtKB/TrEMBL
    A0A087X2F6
    Related
    ENSP00000484945.1, ENST00000432056.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    48720802..48724758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524747.2XP_011523049.1  putative protein PRAC2 isoform X1

    See identical proteins and their annotated locations for XP_011523049.1

    UniProtKB/Swiss-Prot
    D3DTV9
  2. XM_006721865.3XP_006721928.1  putative protein PRAC2 isoform X1

    See identical proteins and their annotated locations for XP_006721928.1

    UniProtKB/Swiss-Prot
    D3DTV9
  3. XM_011524748.1XP_011523050.1  putative protein PRAC2 isoform X1

    See identical proteins and their annotated locations for XP_011523050.1

    UniProtKB/Swiss-Prot
    D3DTV9
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