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BPIFB3 BPI fold containing family B member 3 [ Homo sapiens (human) ]

Gene ID: 359710, updated on 23-Nov-2021

Summary

Official Symbol
BPIFB3provided by HGNC
Official Full Name
BPI fold containing family B member 3provided by HGNC
Primary source
HGNC:HGNC:16178
See related
Ensembl:ENSG00000186190 MIM:615717
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RYA3; LPLUNC3; C20orf185
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See BPIFB3 in Genome Data Viewer
Location:
20q11.21
Exon count:
16
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 20 NC_000020.11 (33053903..33073847)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (31641709..31661653)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene BPI fold containing family B member 6 Neighboring gene pseudouridine 5'-phosphatase pseudogene 3 Neighboring gene BPI fold containing family B member 4 Neighboring gene uncharacterized LOC105372714

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in innate immune response NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BPI fold-containing family B member 3
Names
ligand-binding protein RYA3
long palate, lung and nasal epithelium carcinoma-associated protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001376932.3NP_001363861.2  BPI fold-containing family B member 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL121756
    Conserved Domains (1) summary
    cl00188
    Location:272470
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
  2. NM_182658.5NP_872599.2  BPI fold-containing family B member 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL121756
    Consensus CDS
    CCDS13212.1
    Related
    ENSP00000364643.3, ENST00000375494.3
    Conserved Domains (1) summary
    cl00188
    Location:272470
    BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p13 Primary Assembly

    Range
    33053903..33073847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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