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Cyp9b1 Cytochrome P450 9b1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35634, updated on 4-Jan-2025

Summary

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Official Symbol
Cyp9b1provided by FlyBase
Official Full Name
Cytochrome P450 9b1provided by FlyBase
Primary source
FLYBASE:FBgn0015038
Locus tag
Dmel_CG4485
See related
AllianceGenome:FB:FBgn0015038
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
9b1; CG4485; CYP9B1; Dmel\CG4485; P-450; P450
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; essential hypertension; familial Mediterranean fever; and leukemia (multiple). Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Cyp9b1 in Genome Data Viewer
Location:
42F2-42F2; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7127838..7129808, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3015343..3017313, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Threonine-AGT 2-1 Neighboring gene transfer RNA:Threonine-AGT 1-2 Neighboring gene uncharacterized protein Neighboring gene espinas Neighboring gene long non-coding RNA:CR44443 Neighboring gene Cytochrome P450 9b2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytochrome P450 monooxygenases and insecticide resistance in insects. Bergé JB, et al. Philos Trans R Soc Lond B Biol Sci, 1998 Oct 29. PMID 10021770, Free PMC Article
  2. Identification and characterization of CYPs induced in the Drosophila antenna by exposure to a plant odorant. Baldwin SR, et al. Sci Rep, 2021 Oct 15. PMID 34654888, Free PMC Article
  3. Cytochrome P450 gene clusters in Drosophila melanogaster. Dunkov BC, et al. Mol Gen Genet, 1996 Jun 12. PMID 8676871
  4. HIF- and non-HIF-regulated hypoxic responses require the estrogen-related receptor in Drosophila melanogaster. Li Y, et al. PLoS Genet, 2013. PMID 23382692, Free PMC Article
  5. Effects of the adenylate cyclase activator forskolin and its inactive derivative 1,9-dideoxyforskolin on insect cytochrome P-450 dependent steroid hydroxylase activity. Keogh DP, et al. Experientia, 1992 Jan 15. PMID 1737575

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cytochrome P450 9b1
Names
CG4485-PA
Cyp9b1-PA
cytochrome P450-9b1
NP_523645.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7127838..7129808 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078921.4 → NP_523645.1  cytochrome P450 9b1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523645.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24122, Q9V4I0
    UniProtKB/TrEMBL
    Q8SZ93
    Related
    FBpp0088127
    Conserved Domains (1) summary
    cl12078
    Location:37 → 478
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3YND0 Q3YND0
Q8SZ93 Q8SZ93
Q9V4I0.1 Q9V4I0

Gene LinkOut

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