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CG7882 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35520, updated on 4-Jan-2025

Summary

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Official Symbol
CG7882provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033047
Locus tag
Dmel_CG7882
See related
AllianceGenome:FB:FBgn0033047
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7882
Summary
Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be active in membrane. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in epilepsy (multiple); glucose metabolism disease (multiple); glycogen storage disease; myelomeningocele; and obesity. Orthologous to several human genes including SLC2A1 (solute carrier family 2 member 1); SLC2A2 (solute carrier family 2 member 2); and SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG7882 in Genome Data Viewer
Location:
42A4-42A4; 2-55 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5957621..5960183)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1845126..1847688)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44126 Neighboring gene antisense RNA:CR46269 Neighboring gene long non-coding RNA:CR44127 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial Dysfunction Plus High-Sugar Diet Provokes a Metabolic Crisis That Inhibits Growth. Kemppainen E, et al. PLoS One, 2016. PMID 26812173, Free PMC Article
  2. Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe. Mattila J, et al. Cell Rep, 2015 Oct 13. PMID 26440885
  3. Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging. Huang J, et al. PNAS Nexus, 2023 Dec. PMID 38059264, Free PMC Article
  4. The Female Post-Mating Response Requires Genes Expressed in the Secondary Cells of the Male Accessory Gland in Drosophila melanogaster. Sitnik JL, et al. Genetics, 2016 Mar. PMID 26746709, Free PMC Article
  5. Updates on ion and water transport by the Malpighian tubule. Dow JAT, et al. Curr Opin Insect Sci, 2021 Oct. PMID 33705976, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables hexose transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monosaccharide transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7882-PA
CG7882-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5957621..5960183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136345.2 → NP_610189.2  uncharacterized protein Dmel_CG7882, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610189.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6I4, Q0IGX4
    Conserved Domains (2) summary
    cd06174
    Location:95 → 480
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:43 → 491
    Sugar_tr; Sugar (and other) transporter

  2. NM_165450.3 → NP_724438.1  uncharacterized protein Dmel_CG7882, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724438.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z6I4, Q0IGX4
    Related
    FBpp0085319
    Conserved Domains (2) summary
    cd06174
    Location:95 → 480
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    pfam00083
    Location:43 → 491
    Sugar_tr; Sugar (and other) transporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0IGX4 Q0IGX4

Gene LinkOut

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