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Or42b Odorant receptor 42b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35516, updated on 29-Dec-2023

Summary

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Official Symbol
Or42bprovided by FlyBase
Official Full Name
Odorant receptor 42bprovided by FlyBase
Primary source
FLYBASE:FBgn0033043
Locus tag
Dmel_CG12754
See related
AllianceGenome:FB:FBgn0033043
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
41E.1; 42b; CG12754; Dmel\CG12754; DOR118; Or42; OR42b
Summary
Enables olfactory receptor activity. Involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in adult olfactory receptor neuron Or42b; antennal basiconic sensillum ab1; antennal lobe glomerulus DM1; larval antennal lobe glomerulus 42b; and larval olfactory receptor neuron Or42b. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Or42b in Genome Data Viewer
Location:
41F11-41F11; 2-55 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5797195..5798512, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1684700..1686017, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Odorant receptor 42a Neighboring gene Tetraspanin 42A Neighboring gene defective proboscis extension response 12 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mini-brain computations converting dynamic olfactory inputs into orientation behavior. Louis M. Curr Opin Neurobiol, 2020 Oct. PMID 31837503, Free PMC Article
  2. Ethanol Regulates Presynaptic Activity and Sedation through Presynaptic Unc13 Proteins in Drosophila. Xu S, et al. eNeuro, 2018 May-Jun. PMID 29911175, Free PMC Article
  3. Minute Impurities Contribute Significantly to Olfactory Receptor Ligand Studies: Tales from Testing the Vibration Theory. Paoli M, et al. eNeuro, 2017 May-Jun. PMID 28670618, Free PMC Article
  4. Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit. Kepchia D, et al. PLoS One, 2017. PMID 28562598, Free PMC Article
  5. Metabolite exchange between microbiome members produces compounds that influence Drosophila behavior. Fischer CN, et al. Elife, 2017 Jan 9. PMID 28068220, Free PMC Article

See all (119) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
  
involved_in sensory perception of smell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
odorant receptor 42b
Names
CG12754-PA
Or42b-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5797195..5798512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078900.2 → NP_523624.2  odorant receptor 42b [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523624.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9V9I4
    UniProtKB/TrEMBL
    E2E4L5, E2E4L6, E2E4M2, E2E4M3, E2E4M5, E2E4N7, E2E4P8
    Related
    FBpp0085387, FBtr0086051
    Conserved Domains (1) summary
    pfam02949
    Location:76 → 381
    7tm_6; 7tm Odorant receptor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V9I4.2 Q9V9I4

Gene LinkOut

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