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Tc00.1047053504839.44 tryparedoxin peroxidase [ Trypanosoma cruzi ]

Gene ID: 3539240, updated on 23-Nov-2023
Gene symbol
Tc00.1047053504839.44
Gene description
tryparedoxin peroxidase
Locus tag
Tc00.1047053504839.44
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Trypanosoma cruzi (strain: CL Brener)
Lineage
Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum
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See Tc00.1047053504839.44 in Genome Data Viewer
Location:
chromosome: Unknown
Exon count:
1

NW_001849144.1Genomic Context describing neighboring genes Neighboring gene tryparedoxin peroxidase, putative Neighboring gene hypothetical protein Neighboring gene nucleosome assembly protein-like protein, putative Neighboring gene hypothetical protein

Genomic Sequence:
NW_001849144.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Evaluation of the immune response against Trypanosoma cruzi cytosolic tryparedoxin peroxidase in human natural infection. Girard MC, et al. Immunology, 2018 Nov. PMID 29972690, Free PMC Article
  2. Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite. Piacenza L, et al. Biochem J, 2008 Mar 1. PMID 17973627, Free PMC Article
  3. The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020725
  4. Comparative genomics of trypanosomatid parasitic protozoa. El-Sayed NM, et al. Science, 2005 Jul 15. PMID 16020724
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. results show that c-TXNPx fails to induce a strong immune response in natural infection, being measurable only in those patients without any clinical symptoms.
    Title: Evaluation of the immune response against Trypanosoma cruzi cytosolic tryparedoxin peroxidase in human natural infection.
  2. Identificatoni of components of the antioxidant enzyme network of Trypanosoma cruzi as virulence factors of emerging importance.
    Title: Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite.
Submit: New GeneRIF Correction

Homology

  • heterozygous, non-Esmeraldo-like haplotype

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thioredoxin peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tryparedoxin peroxidase
XP_808754.1
  • 99.0% identical to GB:CAA09922.1: tryparedoxin peroxidase homologue {Trypanosoma cruzi} (PMID: 10713147)
    heterozygous, non-Esmeraldo-like haplotype

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NW_001849144.1 Reference assembly

    Range
    8971..9570 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_803661.1 → XP_808754.1  tryparedoxin peroxidase [Trypanosoma cruzi]

    See identical proteins and their annotated locations for XP_808754.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2V2UHE6, A0A2V2W573, Q4D2Z9
    Conserved Domains (1) summary
    PTZ00253
    Location:1 → 199
    PTZ00253; tryparedoxin peroxidase; Provisional
Nucleotide Protein
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