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Egfl7 EGF-like domain 7 [ Mus musculus (house mouse) ]

Gene ID: 353156, updated on 23-Jun-2021

Summary

Official Symbol
Egfl7provided by MGI
Official Full Name
EGF-like domain 7provided by MGI
Primary source
MGI:MGI:2449923
See related
Ensembl:ENSMUSG00000026921
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
VE-s; Zneu; Zneu1; VE-statin
Expression
Biased expression in lung adult (RPKM 371.9), subcutaneous fat pad adult (RPKM 89.0) and 13 other tissues See more
Orthologs
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Genomic context

See Egfl7 in Genome Data Viewer
Location:
2; 2 A3
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (26471095..26482694)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (26581083..26592682)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (26436576..26448202)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 35978 Neighboring gene predicted gene, 36171 Neighboring gene microRNA 126a Neighboring gene microRNA 126b Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) Neighboring gene predicted gene, 39772

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables Notch binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables calcium ion binding NAS
Non-traceable Author Statement
more info
PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in collagen-containing extracellular matrix HDA PubMed 
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
epidermal growth factor-like protein 7
Names
EGF-like protein 7
NEU1 protein
NOTCH4-like protein
multiple EGF-like domains protein 7
multiple epidermal growth factor-like domains protein 7
vascular endothelial statin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164564.2NP_001158036.2  epidermal growth factor-like protein 7 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732311, BX649422
    Consensus CDS
    CCDS15807.3
    Related
    ENSMUSP00000159032.2, ENSMUST00000239075.2
    Conserved Domains (4) summary
    PRK00591
    Location:197222
    prfA; peptide chain release factor 1; Validated
    cd00054
    Location:111136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07546
    Location:4294
    EMI; EMI domain
    pfam07645
    Location:138177
    EGF_CA; Calcium-binding EGF domain
  2. NM_178444.5NP_848538.4  epidermal growth factor-like protein 7 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732311, BX649422
    Consensus CDS
    CCDS15807.3
    Related
    ENSMUSP00000128741.4, ENSMUST00000166920.10
    Conserved Domains (4) summary
    PRK00591
    Location:197222
    prfA; peptide chain release factor 1; Validated
    cd00054
    Location:111136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07546
    Location:4294
    EMI; EMI domain
    pfam07645
    Location:138177
    EGF_CA; Calcium-binding EGF domain
  3. NM_198724.3NP_942017.3  epidermal growth factor-like protein 7 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732311, BX649422
    Consensus CDS
    CCDS15807.3
    Related
    ENSMUSP00000099971.7, ENSMUST00000102907.13
    Conserved Domains (4) summary
    PRK00591
    Location:197222
    prfA; peptide chain release factor 1; Validated
    cd00054
    Location:111136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07546
    Location:4294
    EMI; EMI domain
    pfam07645
    Location:138177
    EGF_CA; Calcium-binding EGF domain
  4. NM_198725.3NP_942018.3  epidermal growth factor-like protein 7 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL732311, BX649422
    Consensus CDS
    CCDS15808.3
    Related
    ENSMUSP00000097863.7, ENSMUST00000100290.13
    Conserved Domains (4) summary
    PRK00591
    Location:197222
    prfA; peptide chain release factor 1; Validated
    cd00054
    Location:111136
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07546
    Location:4294
    EMI; EMI domain
    pfam07645
    Location:138177
    EGF_CA; Calcium-binding EGF domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    26471095..26482694
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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