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LCE3A late cornified envelope 3A [ Homo sapiens (human) ]

Gene ID: 353142, updated on 13-May-2022

Summary

Official Symbol
LCE3Aprovided by HGNC
Official Full Name
late cornified envelope 3Aprovided by HGNC
Primary source
HGNC:HGNC:29461
See related
Ensembl:ENSG00000185962 MIM:612613; AllianceGenome:HGNC:29461
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP13
Summary
Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and killing of cells of other organism. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See LCE3A in Genome Data Viewer
Location:
1q21.3
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152622834..152623103, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151759380..151759649, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152595310..152595579, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope 3C Neighboring gene late cornified envelope 3B Neighboring gene late cornified envelope pseudogene 4 Neighboring gene long intergenic non-protein coding RNA 302 Neighboring gene late cornified envelope pseudogene 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
late cornified envelope protein 3A
Names
late envelope protein 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178431.1NP_848518.1  late cornified envelope protein 3A

    See identical proteins and their annotated locations for NP_848518.1

    Status: VALIDATED

    Source sequence(s)
    AL139247
    Consensus CDS
    CCDS1017.1
    UniProtKB/Swiss-Prot
    Q5TA76
    Related
    ENSP00000335006.1, ENST00000335674.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152622834..152623103 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151759380..151759649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)