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LCE1F late cornified envelope 1F [ Homo sapiens (human) ]

Gene ID: 353137, updated on 7-Apr-2024

Summary

Official Symbol
LCE1Fprovided by HGNC
Official Full Name
late cornified envelope 1Fprovided by HGNC
Primary source
HGNC:HGNC:29467
See related
Ensembl:ENSG00000240386 MIM:612608; AllianceGenome:HGNC:29467
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP6
Summary
Enables identical protein binding activity. Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See LCE1F in Genome Data Viewer
Location:
1q21.3
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152775140..152777024)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151911685..151913569)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152747616..152749500)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope pseudogene 1 Neighboring gene keratinocyte proline rich protein Neighboring gene ReSE screen-validated silencer GRCh37_chr1:152740212-152740401 Neighboring gene late cornified envelope 1E Neighboring gene late cornified envelope 1D

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in keratinization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
late cornified envelope protein 1F
Names
late envelope protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178354.3NP_848131.1  late cornified envelope protein 1F

    See identical proteins and their annotated locations for NP_848131.1

    Status: VALIDATED

    Source sequence(s)
    AL353779
    Consensus CDS
    CCDS1023.1
    UniProtKB/Swiss-Prot
    Q5T754
    Related
    ENSP00000334187.2, ENST00000334371.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152775140..152777024
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151911685..151913569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)