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LCE1C late cornified envelope 1C [ Homo sapiens (human) ]

Gene ID: 353133, updated on 23-Nov-2021

Summary

Official Symbol
LCE1Cprovided by HGNC
Official Full Name
late cornified envelope 1Cprovided by HGNC
Primary source
HGNC:HGNC:29464
See related
Ensembl:ENSG00000197084 MIM:612605
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP3
Expression
Restricted expression toward skin (RPKM 108.0) See more
Orthologs
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Genomic context

See LCE1C in Genome Data Viewer
Location:
1q21.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (152804832..152806651, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152777308..152779127, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope 1E Neighboring gene late cornified envelope 1D Neighboring gene late cornified envelope 1B Neighboring gene late cornified envelope 1A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in keratinization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
late cornified envelope protein 1C
Names
late envelope protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276331.2NP_001263260.1  late cornified envelope protein 1C isoform 2

    See identical proteins and their annotated locations for NP_001263260.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame segment compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AL353779
  2. NM_178351.4NP_848128.1  late cornified envelope protein 1C isoform 1

    See identical proteins and their annotated locations for NP_848128.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL353779
    Consensus CDS
    CCDS1026.1
    UniProtKB/Swiss-Prot
    Q5T751
    Related
    ENSP00000475270.1, ENST00000607093.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    152804832..152806651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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