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LCE1C late cornified envelope 1C [ Homo sapiens (human) ]

Gene ID: 353133, updated on 13-May-2022

Summary

Official Symbol
LCE1Cprovided by HGNC
Official Full Name
late cornified envelope 1Cprovided by HGNC
Primary source
HGNC:HGNC:29464
See related
Ensembl:ENSG00000197084 MIM:612605; AllianceGenome:HGNC:29464
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LEP3
Summary
Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward skin (RPKM 108.0) See more
Orthologs
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Genomic context

See LCE1C in Genome Data Viewer
Location:
1q21.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (152804832..152806651, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (151941383..151943202, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (152777308..152779127, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene late cornified envelope 1E Neighboring gene late cornified envelope 1D Neighboring gene late cornified envelope 1B Neighboring gene late cornified envelope 1A

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in keratinization IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
late cornified envelope protein 1C
Names
late envelope protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276331.2NP_001263260.1  late cornified envelope protein 1C isoform 2

    See identical proteins and their annotated locations for NP_001263260.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame segment compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AL353779
  2. NM_178351.4NP_848128.1  late cornified envelope protein 1C isoform 1

    See identical proteins and their annotated locations for NP_848128.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AL353779
    Consensus CDS
    CCDS1026.1
    UniProtKB/Swiss-Prot
    Q5T751
    Related
    ENSP00000475270.1, ENST00000607093.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    152804832..152806651 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    151941383..151943202 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)