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CTSC cathepsin C [ Bos taurus (cattle) ]

Gene ID: 352958, updated on 20-Jun-2021

Summary

Official Symbol
CTSCprovided by VGNC
Official Full Name
cathepsin Cprovided by VGNC
Primary source
VGNC:VGNC:27814
See related
BGD:BT28669; Ensembl:ENSBTAG00000011100
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
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Genomic context

See CTSC in Genome Data Viewer
Location:
chromosome: 29
Exon count:
9
Annotation release Status Assembly Chr Location
106 current ARS-UCD1.2 (GCF_002263795.1) 29 NC_037356.1 (7375382..7415746)
105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 29 AC_000186.1 (7433445..7473316)

Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444873 Neighboring gene histone H2B type 1-J Neighboring gene uncharacterized LOC104976218 Neighboring gene RAB38, member RAS oncogene family

Genomic regions, transcripts, and products

General gene information

Markers

Homology

Clone Names

  • MGC126959

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables dipeptidyl-peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in zymogen activation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dipeptidyl peptidase 1
Names
DPP-I
DPPI
cathepsin J
dipeptidyl peptidase I
dipeptidyl transferase
NP_001028789.1
XP_010819111.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033617.2NP_001028789.1  dipeptidyl peptidase 1 precursor

    See identical proteins and their annotated locations for NP_001028789.1

    Status: PROVISIONAL

    Source sequence(s)
    BC102115
    UniProtKB/Swiss-Prot
    Q3ZCJ8
    Related
    ENSBTAP00000014735.4, ENSBTAT00000014735.5
    Conserved Domains (2) summary
    cd02621
    Location:231460
    Peptidase_C1A_CathepsinC; Cathepsin C; also known as Dipeptidyl Peptidase I (DPPI), an atypical papain-like cysteine peptidase with chloride dependency and dipeptidyl aminopeptidase activity, resulting from its tetrameric structure which limits substrate access. Each subunit of ...
    pfam08773
    Location:26138
    CathepsinC_exc; Cathepsin C exclusion domain

RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD1.2 Primary Assembly

Genomic

  1. NC_037356.1 Reference ARS-UCD1.2 Primary Assembly

    Range
    7375382..7415746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010820809.3XP_010819111.1  dipeptidyl peptidase 1 isoform X1

    Conserved Domains (1) summary
    pfam08773
    Location:26106
    CathepsinC_exc; Cathepsin C exclusion domain
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